licopyranocoumarin
- CAS No.
- 117038-80-9
- Chemical Name:
- licopyranocoumarin
- Synonyms
- licopyranocoumarin;3-(2,4-Dihydroxyphenyl)-8-(hydroxymethyl)-5-methoxy-8-methyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one;(+)-3-(2,4-Dihydroxyphenyl)-8-(hydroxymethyl)-6,7-dihydro-8-methyl-5-methoxy-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one
- CBNumber:
- CB41354997
- Molecular Formula:
- C21H20O7
- Molecular Weight:
- 384.38
- MDL Number:
- MOL File:
- 117038-80-9.mol
| Boiling point | 675.3±55.0 °C(Predicted) |
|---|---|
| Density | 1.397±0.06 g/cm3(Predicted) |
| pka | 8.89±0.40(Predicted) |
| FDA UNII | 4X8VZO798F |
licopyranocoumarin Chemical Properties,Uses,Production
Uses
Licopyranocoumarin is an isoflavonoid that shows CYP3A4 inhibitory activity with an IC50 of 32 μM. Licopyranocoumarin has potent neuroprotective activities[1].
Definition
ChEBI: Licopyranocoumarin is an isoflavonoid and an organic hydroxy compound.
IC 50
CYP3A4: 32 μM (IC50)
References
[1] Takahiro Fujimaki, et al. Identification of licopyranocoumarin and glycyrurol from herbal medicines as neuroprotective compounds for Parkinson's disease. PLoS One. 2014 Jun 24;9(6):e100395. DOI:10.1371/journal.pone.0100395
[2] Sachiko Tsukamoto, et al. CYP3A4 inhibitors isolated from Licorice. Biol Pharm Bull. 2005 Oct;28(10):2000-2. DOI:10.1248/bpb.28.2000
licopyranocoumarin Preparation Products And Raw materials
Raw materials
Preparation Products
licopyranocoumarin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 8914 | 60 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 18108052721 | 2850505130@qq.com | China | 5173 | 58 |
| Shanghai Hewu Biotechnology Co., LTD | 021-57886085 17317861055 | shhebio@126.com | CHINA | 7974 | 58 |
| Foshan Treasure Biotechnology Co., Ltd | 0757-85921206 18520245316 | 2329783215@qq.com | China | 12661 | 58 |
| Chengdu Push Bio-Technology Co., Ltd. | 18080489829 | 3004654993@qq.com | China | 9209 | 58 |
| Beijing PUXI Technology Co., Ltd | 400-8087372 13161114455 | puxi_sale@qq.com | China | 4990 | 58 |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | sales@szzxbio.com | China | 2976 | 58 |