orexin B
- CAS No.
- 205599-76-4
- Chemical Name:
- orexin B
- Synonyms
- orexin B;Rabbit Anti-Orexin B antibody
- CBNumber:
- CB41360705
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01635376
- MOL File:
- Mol file
orexin B price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | O6262 | Orexin B rat, mouse ≥97% (HPLC) | 205599-76-4 | 0.5MG | $1110 | 2024-03-01 | Buy |
Sigma-Aldrich | O6262 | Orexin B rat, mouse ≥97% (HPLC) | 205599-76-4 | 0.1MG | $269 | 2023-06-20 | Buy |
Alfa Aesar | J65110 | Orexin B human | 205599-76-4 | 0.5mg | $232 | 2023-06-20 | Buy |
Alfa Aesar | J65110 | Orexin B human | 205599-76-4 | 1mg | $404 | 2023-06-20 | Buy |
orexin B Chemical Properties,Uses,Production
Uses
Orexin is a neuropeptide that modulates the energy and metabolism balance. The effects of orexin are mediated by one of the two G protein-coupled receptors, orexin receptor 1 or 2. OXRs are expressed in oxinergic projection areas of the brain and regulate food intake by reducing systemic and brain signals that drive over-eating. Synthetic peptide corresponding to the C-terminus of human orexin receptor 1, conjugated to KLH. The immunizing peptide has 70% homology with the rat and mouse gene.
Uses
Orexin B rat, mouse has been used to test its effect on social interaction in the stress-resilient mice.
General Description
Orexin A, also known as hypocretin 1 (hcrt1), is a 33 amino acid excitatory neuropeptide, localized in a small set of neurons in the perifornical area of the hypothalamus. It is synthesized from the precursor protein prepro-orexin in neurons. Orexin A binds to its G-protein-coupled receptor orexin-1 (OX1), which is also called as hcrt receptors 1 (hcrtr1).
Biochem/physiol Actions
Orexins (hypocretins) comprise a family of hypothalamic peptides that are involved in the initiation of sleep and in feeding behavior. Orexin A stimulates food intake through activation of the OX1 receptor. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons.
orexin B Preparation Products And Raw materials
Raw materials
Preparation Products
orexin B Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Anyan Biological Technology Co., Ltd. | 025-52151215 13915956535 13915956535 | 570945402@qq.com | China | 9733 | 58 |
Beijing Boorsen Biotechnology Co., Ltd | 400-901-9800 18611424007 | cis@bioss.com.cn | China | 9518 | 58 |
Supplier | Advantage |
---|---|
Nanjing Anyan Biological Technology Co., Ltd. | 58 |
Beijing Boorsen Biotechnology Co., Ltd | 58 |