DINOPROSTONE ETHANOLAMIDE
- CAS No.
- 194935-38-1
- Chemical Name:
- DINOPROSTONE ETHANOLAMIDE
- Synonyms
- PGE2-EA;DINOPROSTONE ETHANOLAMIDE;PROSTAGLANDIN E2 ETHANOLAMIDE;Prostaglandin E2 Ethanolamide Exclusive;Prostaglandin E2 Ethanolamide MaxSpecStandard;Prostaglandin E2 Ethanolamide Lipid Maps MS Standard;N-(2-HYDROXYETHYL)-9-OXO-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE;Prosta-5,13-dien-1-amide, 11,15-dihydroxy-N-(2-hydroxyethyl)-9-oxo-, (5Z,11α,13E,15S)-;(Z)-N-(2-hydroxyethyl)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enamide
- CBNumber:
- CB4146591
- Molecular Formula:
- C22H37NO5
- Molecular Weight:
- 395.53
- MDL Number:
- MFCD00797645
- MOL File:
- 194935-38-1.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
DINOPROSTONE ETHANOLAMIDE price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 14012 | Prostaglandin E2 Ethanolamide ≥98% | 194935-38-1 | 500μg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 10007212 | Prostaglandin E2 Ethanolamide MaxSpec? Standard ≥95% | 194935-38-1 | 100μg | $68 | 2023-06-20 | Buy |
| Cayman Chemical | 14012 | Prostaglandin E2 Ethanolamide ≥98% | 194935-38-1 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 14012 | Prostaglandin E2 Ethanolamide ≥98% | 194935-38-1 | 5mg | $254 | 2024-03-01 | Buy |
| Cayman Chemical | 14012 | Prostaglandin E2 Ethanolamide ≥98% | 194935-38-1 | 10mg | $443 | 2024-03-01 | Buy |
DINOPROSTONE ETHANOLAMIDE Chemical Properties,Uses,Production
Description
Prostaglandin E2 ethanolamide (PGE2-EA) is an analog of PGE2 with improved water solubility and stability. PGE2-EA is formed via COX-2 metabolism of arachidonoyl ethanolamide (AEA; ) and acts as an agonist at E prostanoid (EP) receptors 1-4 (Kis = 2.45, 0.46, 0.2, and 0.51 μM, respectively). It also inhibits indoleamine 2,3-dioxygenase-1 (IDO-1) in THP-1 cells and human monocytes (IC50s = 5.7 and 4.7 μM, respectively). PGE2-EA (10 μM) prevents morphological changes and F-actin rearrangement as well as reduces L-homocysteine-induced NLRP3 inflammasome formation and activation in podocytes. Ex vivo, PGE2-EA reduces luminal damage and lymphocyte infiltration in a human mucosal explant colitis model.
Uses
Prostaglandin E2 Ethanolamide-d4 is the isotope labelled analogue of Prostaglandin E2 Ethanolamide, an analogue of Prostaglandin E2 (P838610). Prostaglandin E2 is most common and most biologically potent of mammalian prostaglandins.
Definition
ChEBI: Prostaglandin E2 ethanolamide is a prostanoid.
DINOPROSTONE ETHANOLAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
DINOPROSTONE ETHANOLAMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25009 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11975 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12582 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 16377 | 58 |