ChemicalBook >> CAS DataBase List >>5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE

CAS No.
213252-19-8
Chemical Name:
5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE
Synonyms
L410198;L 410198;5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE;5-[(2,4-dioxothiazolidin-5-yl)Methyl]-2-Methoxy-N-[[4-(trifluoroMethyl)phenyl]Methyl]benzaMide;Benzamide, 5-[(2,4-dioxo-5-thiazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]-
CBNumber:
CB41477812
Molecular Formula:
C20H17F3N2O4S
Molecular Weight:
438.42
MDL Number:
MFCD00953587
MOL File:
213252-19-8.mol
Last updated:2023-05-21 10:59:17

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE Properties

storage temp. -20°C
solubility DMSO: 10 mg/ml
form A solid

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation HCH0134359 5-(2,4-DIOXO-THIAZOLIDIN-5-YLMETHYL)-2-METHOXY-N-(4-TRIFLUOROMETHYL-BENZYL)-BENZAMIDE 95.00% 213252-19-8 5MG $504.36 2021-12-16 Buy
Product number Packaging Price Buy
HCH0134359 5MG $504.36 Buy

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE Chemical Properties,Uses,Production

Biological Activity

KRP 927 is a thiazolidinedione dual agonist of PPARα and PPARγ (EC50s = 149 and 83 nM, respectively, in transactivation assays).1 It decreases hyperglycemia and hyperinsulinemia in ob/ob mice in a dose-dependent manner. KRP 927 (10 or 30 mg/kg) reduces serum total cholesterol and triglyceride levels in hamsters.

References

1.Doebber, T.W., Kelly, L.J., Zhou, G., et al.MK-0767, a novel dual PPARα/γ agonist, displays robust antihyperglycemic and hypolipidemic activitiesBiochem. Biophys. Res. Commun.318(2)323-328(2004)

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE Suppliers

Global( 10)Suppliers
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ShangHai Onsyn-Chemical Technology Co., Ltd. 021-58359326 13124831025 angsihuaxue@126.com China 246 55
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 sales-cpd@caerulumpharma.com China 3453 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5594 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29990 58
5-[(2,4-DIOXO-1,3-THIAZOLIDIN-5-YL)METHYL]-2-METHOXY-N-[4-(TRIFLUOROMETHYL)BENZYL]BENZAMIDE 5-[(2,4-dioxothiazolidin-5-yl)Methyl]-2-Methoxy-N-[[4-(trifluoroMethyl)phenyl]Methyl]benzaMide Benzamide, 5-[(2,4-dioxo-5-thiazolidinyl)methyl]-2-methoxy-N-[[4-(trifluoromethyl)phenyl]methyl]- L 410198 L410198 213252-19-8