ISOXANTHOHUMOL
- CAS No.
- 521-48-2
- Chemical Name:
- ISOXANTHOHUMOL
- Synonyms
- ISOXANTHOHUMOL;4',7-DIHYDROXY-5-METHOXY-8-PRENYLFLAVANONE;4',7-Dihydroxy-5-methoxy-8-(3-methyl-2-butenyl)flavanone;2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;2-(4-Hydroxyphenyl)-5-methoxy-7-hydroxy-8-(3-methyl-2-butenyl)-2,3-dihydro-4H-1-benzopyran-4-one;2,3-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methyl-2-buten-1-yl)-
- CBNumber:
- CB4150547
- Molecular Formula:
- C21H22O5
- Molecular Weight:
- 354.4
- MDL Number:
- MFCD00238718
- MOL File:
- 521-48-2.mol
ISOXANTHOHUMOL price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SMB00389 | Isoxanthohumol ≥99% (HPLC) | 521-48-2 | 1mg | $120 | 2024-03-01 | Buy |
| Sigma-Aldrich | 55423 | Isoxanthohumol analytical standard | 521-48-2 | 5mg | $513 | 2022-05-15 | Buy |
| Cayman Chemical | 23233 | Isoxanthohumol ≥98% | 521-48-2 | 500μg | $35 | 2024-03-01 | Buy |
| Cayman Chemical | 23233 | Isoxanthohumol ≥98% | 521-48-2 | 1mg | $63 | 2024-03-01 | Buy |
| Cayman Chemical | 23233 | Isoxanthohumol ≥98% | 521-48-2 | 5mg | $245 | 2024-03-01 | Buy |
ISOXANTHOHUMOL Chemical Properties,Uses,Production
Description
Isoxanthohumol is a natural, prenylated chalcone isolated from the hop plant, H. lupulus (hops). It has diverse biological activities, including antiproliferative, anti-inflammatory, and antiviral properties. In B16 and A375 melanoma cells, isoxanthohumol inhibits proliferation (IC50s = 22.15 and 22.9 μM in an MTT assay), slows cell division, and induces apoptosis. Isoxanthohumol reversibly inhibits Kv1.3 channels with an EC50 value of 7.8 μM in human Jurkat T cells using patch clamp electrophysiology. It has strong deterrent properties against the peach potato aphid. It has also been used as a marker of beer consumption. Isoxanthohumol is metabolized in the liver and intestine to 8-prenylnaringenin , a potent phytoestrogen.
Uses
Isoxanthohumol is a prenylated flavone isolated from hop. A chromane-like cyclic prenylflavonoids for neurological disorder therapy. Isoxanthohumol is a prenylated flavonoid phytoestrogen which is an apoptosis inducer in mature adipocytes
Definition
ChEBI: Isoxanthohumol is a member of flavanones.
ISOXANTHOHUMOL Preparation Products And Raw materials
Raw materials
Preparation Products
ISOXANTHOHUMOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 3942 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10473 | 58 |
| Protheragen-ING | +16313385890 | info@protheragen-ing.com | United States | 3868 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20283 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Nanjing Spring & Autumn Biological Engineering Co., Ltd. | 025-84430028 13815430202 | sale02@cqherb.com | China | 281 | 59 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |