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3-Chloro-4-fluoroaniline

3-Chloro-4-fluoroaniline structure

CAS No.: 367-21-5

Chemical Name:: 3-Chloro-4-fluoroaniline

Synonyms: 3-CHLORO-4-FLUORO-PHENYLAMINE;3-CHLORO-4-FLUOROBENZENAMINE;NSC 10290;3-Chloro-4-flu;AKOS BBS-00003577;Chloro-4-fluoroanil;Fluorochloroaniline;Gefitinib IMpurity V;3-Chloro-4-fluoroani;Gefitinib Impurity K

CBNumber:: CB4182681

Molecular Formula:: C6H5ClFN

Molecular Weight:: 145.56

MDL Number:: MFCD00007767

MOL File:: 367-21-5.mol

MSDS File:: SDS

Last updated:2024-12-18 14:07:02

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3-Chloro-4-fluoroaniline Properties

Melting point	42-44 °C (lit.)
Boiling point	227-228 °C (lit.)
Density	1,226 g/cm³
vapor pressure	0.01 hPa (20 °C)
refractive index	1,54-1,542
Flash point	>230 °F
storage temp.	Store below +30°C.
solubility	10g/l
form	Crystalline Solid
pka	3.60±0.10(Predicted)
color	Beige to brown
PH	7 (10g/l, H2O, 20℃)
Water Solubility	10 g/L (20 ºC)
BRN	1562786
Stability	Stable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates. May be air-sensitive.
InChIKey	YSEMCVGMNUUNRK-UHFFFAOYSA-N
CAS DataBase Reference	367-21-5(CAS DataBase Reference)
FDA UNII	7L63CC70UQ
EPA Substance Registry System	3-Chloro-4-fluoroaniline (367-21-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08

Signal word

Danger

Hazard statements

H301+H311+H331-H373

Precautionary statements

P260-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314

Hazard Codes

T,Xi,Xn

Risk Statements

23/24/25-33-36/37/38-20/21/22

Safety Statements

36/37/39-45-26

RIDADR

UN 2811 6.1/PG 2

WGK Germany

9-23

Hazard Note

Irritant/Toxic

TSCA

HazardClass

TOXIC

HazardClass

6.1

PackingGroup

III

HS Code

29214210

Toxicity

LD50 orally in Rabbit: 506 mg/kg

NFPA 704

	0
2		0

3-Chloro-4-fluoroaniline price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	228583	3-Chloro-4-fluoroaniline 98%	367-21-5	25g	$26	2024-03-01	Buy
Sigma-Aldrich	8.18752	3-Chloro-4-fluoroaniline for synthesis	367-21-5	25g	$91.6	2024-03-01	Buy
Sigma-Aldrich	228583	3-Chloro-4-fluoroaniline 98%	367-21-5	100g	$64.2	2024-03-01	Buy
Sigma-Aldrich	8.18752	3-Chloro-4-fluoroaniline for synthesis	367-21-5	100g	$275	2023-01-07	Buy
TCI Chemical	C1024	3-Chloro-4-fluoroaniline >98.0%(GC)	367-21-5	25g	$16	2024-03-01	Buy

Product number	Packaging	Price	Buy
228583	25g	$26	Buy
8.18752	25g	$91.6	Buy
228583	100g	$64.2	Buy
8.18752	100g	$275	Buy
C1024	25g	$16	Buy

3-Chloro-4-fluoroaniline Chemical Properties,Uses,Production

Chemical Properties

dark purple to black solid

Uses

4-Fluoro-3-chloroaniline, is an organic Fluorinated building block used for the synthesis of pharmaceutical and biologically active compounds such as, novel 6-Fluorobenzothiazole-substituted pyrazole analogues, having antiinflammatory activity.

General Description

The exposure of workers to 3-chloro-4-fluoroaniline (CFA) was monitored by an HPLC method.

3-Chloro-4-fluoroaniline synthesis

Synthesis of 3-Chloro-4-fluoroaniline from 3-Chloro-4-fluoronitrobenzene

3-Chloro-4-fluoroaniline Preparation Products And Raw materials

Raw materials

Potassium fluoride Ferric chloride Iron chloride hexahydrate Dimethyl sulfoxide 1,2-Dichlorobenzene

Carbamic acid, (3-chloro-4-fluorophenyl)-, 1,1-dimethylethyl ester 3-Chloro-4-fluoronitrobenzene

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Preparation Products

Norfloxacin Ciprofloxacin hydrochloride 1,3-Dichloro-4-fluorobenzene Ciprofloxacin 2,4-Dichloro-5-fluorobenzoic acid

3-CHLORO-4-FLUOROPHENYL ISOTHIOCYANATE 3-Chloro-4-fluorobenzaldehyde N-(3-chloro-4-fluorophenyl)-7-Methoxy-6-aminoquinazolin-4-aMine indoleaMine-2,3-dioxygenase inhibitor INCB024360 2-Bromo-5-chloro-4-fluoroaniline

N-(3-chloro-4-fluorophenyl)-2-hydroxybenzamide 6-Amino-4-(3-chloro-4-fluoroanilino)quinazoline (3-Chloro-4-fluorophenyl)ethylamine Benzenemethanamine, N-(3-chloro-4-fluorophenyl)-3,4-dimethoxy-

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3-Chloro-4-fluoroaniline Suppliers

Global( 624)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19632	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3959	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12835	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5889	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	973	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20284	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29791	60
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	810	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55

Supplier	Advantage
Aceschem Inc.	58
Hebei Weibang Biotechnology Co., Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Anhui Ruihan Technology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 3-Chloro-4-fluoroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-08	3-Chloro-4-fluoroaniline 367-21-5	US $0.00 / KG	1KG	99%	10 mt	Hebei Weibang Biotechnology Co., Ltd
2024-10-11	3-Chloro-4-Fluorobenzenamine 367-21-5	US $10.00 / KG	1KG	98%	10 ton	Hebei Chuanghai Biotechnology Co,.LTD
2024-06-18	3-Chloro-4-fluoroaniline 367-21-5	US $1.00 / KG	1KG	99%	20t	Shaanxi Dideu Medichem Co. Ltd

3-Chloro-4-fluoroaniline
367-21-5
US $0.00 / KG
99%
Hebei Weibang Biotechnology Co., Ltd

3-Chloro-4-Fluorobenzenamine
367-21-5
US $10.00 / KG
98%
Hebei Chuanghai Biotechnology Co,.LTD

3-Chloro-4-fluoroaniline
367-21-5
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

3-Chloro-4-fluoroaniline Spectrum

3-Chloro-4-fluoroaniline(367-21-5)MS 3-Chloro-4-fluoroaniline(367-21-5)¹HNMR 3-Chloro-4-fluoroaniline(367-21-5)¹³CNMR 3-Chloro-4-fluoroaniline(367-21-5)IR1

367-21-5(3-Chloro-4-fluoroaniline)Related Search:

4-Chloroaniline 2-Chloroaniline 2-Fluoroaniline 3-Aminobenzotrifluoride 4-(Trifluoromethoxy)aniline

3-Fluoroaniline 3-Chloroaniline Chlorpropham 4-Fluoroaniline Epichlorohydrin

4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol 3-chloro-4-nitrophenol 3-(3-morpholinylpropoxy)-4-methoxybenzonitrile Benzaldehyde, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- O-Desmethyl Gefitinib

3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate 4-Defluoro-4-hydroxy Gefitinib Gefitinib Impurity 14

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3－chloro-4-fluoroanilinc 3-CHLORO-4-FLUOROANILINENORFLOXACIN 3-CHLORO-4-FLUOROANILINE pure 3-/4-CHLOROFLUOROANILINE Benzenamine, 3-chloro-4-fluoro- 3-Chloro-4-fluoroaniline 98% Chloro-4-fluoroanil Gefitinib IMpurity V 3-Chloro-4-flu 3-Chloro-4-fluoroaniline,98% 3-Chlor-4-fluoranilin 3-chloro-4-fluoro-benzenamin Fluorochloroaniline 3-CHLORO-4-FLUOROANILINE AKOS BBS-00003577 LABOTEST-BB LTBB000779 4-Fluoro-3-chloroaniline 3-CHLORO-4-FLUOROANILINE OEKANAL, 250 MG 3-Chloro-4-Fluoroaniline99% 3-CHLORO-4-FLUOROANILINE A 3-CHLORO-4-FLUOROANILINE B para-fluoro-Meta-chloroaniline M-Chloro-p-fluoro-aniline NSC 10290 3-CHLORO-4-FLUOROANILINE, 99.5+% 3-Chloro-4-fluoroanaline 3-Chloro-4-fluoroanaline 1g [367-21-5] 3-Chloro-4-fluoroani Gefitinib Impurity K 3-Chloro-4-fluoroaniline > 3-chloro-4-fluoraniline 3-Chloro-4-fluoroaniline(Chunks or pellets) 3-Chloro-4-fluoroaniline ISO 9001：2015 REACH 3-CHLORO-4-FLUOROBENZENAMINE 3-CHLORO-4-FLUORO-PHENYLAMINE Afatinib Impurity 167 367-21-5 Nitrogen Compounds Organic Building Blocks C2 to C6 Building Blocks Amines Furans ,Coumarins Anilines, Aromatic Amines and Nitro Compounds Aniline series Fluorobenzene API Intermediate C2 to C6 Nitrogen Compounds ChloroChemical Class FluoroMore...Close... Alpha Sort Amines Analytical Standards AromaticsChemical Class AromaticsVolatiles/ Semivolatiles C CAlphabetic