13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione

CAS No.
38763-74-5
Chemical Name:
13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione
Synonyms
Swazine;13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione;Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-5(2H),2'-oxirane]-2,7(6H)-dione, 3,4,9,11,13,14,14a,14b-octahydro-6-hydroxy-4,6-dimethyl-3-methylene-, (2'R,4S,6R,14aR,14bR)-
CBNumber:
CB42183198
Molecular Formula:
C18H23NO6
Molecular Weight:
349.38
MDL Number:
MOL File:
38763-74-5.mol
Last updated:2022-12-21 16:56:50

13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione Properties

Melting point 165°C
Boiling point 611.7±55.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 12.78±0.40(Predicted)
FDA UNII DXK68BHZ98

13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione Chemical Properties,Uses,Production

Description

A hepatotoxic alkaloid isolated from Senecio swaziensis Compton, the base yields clusters of colourless crystals from EtOH. It is strongly laevorotatory with [α]20D - 103.5° (c 1.0, EtOH). The ultraviolet spectrum in ethanol has a single broad absorption maximum at 195 mil.

References

Gordon-Gray et al., Tetrahedron Lett., 707 (1972)
Crystal structure: Laing, Sommerville., Tetrahedron Lett., 5183 (1972)

13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione Preparation Products And Raw materials

Raw materials

Preparation Products

13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Sichuan BioCrick Biotech Co., Ltd 28-85433893 info@biocrick.com CHINA 4988 58
13,19-Epoxy-12-hydroxy-14β-methyl-21-norsenecionan-11,16-dione Swazine Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-5(2H),2'-oxirane]-2,7(6H)-dione, 3,4,9,11,13,14,14a,14b-octahydro-6-hydroxy-4,6-dimethyl-3-methylene-, (2'R,4S,6R,14aR,14bR)- 38763-74-5