(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester

CAS No.
6883-09-6
Chemical Name:
(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester
Synonyms
Refractidine;(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester
CBNumber:
CB42226493
Molecular Formula:
C23H28N2O4
Molecular Weight:
396.47942
MDL Number:
MOL File:
6883-09-6.mol

(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester Properties

Melting point 158-l60°C

(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

One of the numerous alkaloids isolated from Aspidosperma species, this base occurs in A. refractum Mart. It is laevorotatory with [α]D - 150° (CHCI3). The ultraviolet spectrum in EtOH is typical of these imidazolidinocarbazole alkaloids with absorption maxima at 208, 253, 278 and 288 mf.1.. The original structure has recently been revised to that given above.

References

Gilbert et ai., Tetrahedron Lett., 59 (1962) Revised structure: Linde., Pharm. Acta Heiv., 45, 248 (1970)

(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(2α,3β,5α,6β)-1-Formyl-6-methoxyaspidofractinine-3-carboxylic acid methyl ester Refractidine 6883-09-6