ChemicalBook >> CAS DataBase List >>Benserazide hydrochloride
Benserazide hydrochloride
- CAS No.
- 14919-77-8
- Chemical Name:
- Benserazide hydrochloride
- Synonyms
- BENSERAZIDE HCL;RO 4-4602;BENPARIZDE;31796-68-6;Ro 4-4602/001;NCGC00093698-03;SPECTRUM1500137;Benserazide hydrochlo;Benserazid hydrochloride;BENSERAZIDE HYDROCHLORIDE
- CBNumber:
- CB4229025
- Molecular Formula:
- C10H16ClN3O5
- Molecular Weight:
- 293.7
- MDL Number:
- MFCD00078571
- MOL File:
- 14919-77-8.mol
- MSDS File:
- SDS
Last updated:2024-11-20 11:41:24
| Melting point | 146°C |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: 10 mg/mL |
| form | solid |
| color | White to Off-White |
| PH | pH(10g/L, 25℃) : 4.0～5.0 |
| Water Solubility | Soluble in water, dimethyl sulfoxide and methanol. Insoluble in ethanol and acetone. |
| Sensitive | Light Sensitive |
| λmax | 272nm(HCl aq.)(lit.) |
| Merck | 14,1050 |
| InChIKey | ULFCBIUXQQYDEI-UHFFFAOYSA-N |
| CAS DataBase Reference | 14919-77-8(CAS DataBase Reference) |
| FDA UNII | B66E5RK36Q |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | VT9632300 | |||||||||
| HS Code | 29280000 | |||||||||
| NFPA 704 |
|
Benserazide hydrochloride price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0002115 | Benserazide for peak identification A European Pharmacopoeia (EP) Reference Standard | 14919-77-8 | Y0002115 | $150 | 2024-03-01 | Buy |
| Sigma-Aldrich | B7283 | Benserazide hydrochloride ≥98% (TLC), solid | 14919-77-8 | 1g | $120 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP685 | Benserazide hydrochloride British Pharmacopoeia (BP) Reference Standard | 14919-77-8 | 100MG | $275 | 2024-03-01 | Buy |
| Sigma-Aldrich | B7283 | Benserazide hydrochloride ≥98% (TLC), solid | 14919-77-8 | 5g | $417 | 2024-03-01 | Buy |
| TCI Chemical | B4108 | Benserazide Hydrochloride >97.0%(HPLC)(T) | 14919-77-8 | 1g | $65 | 2024-03-01 | Buy |
Benserazide hydrochloride Chemical Properties,Uses,Production
Description
Benserazide is an inhibitor of aromatic L-amino acid decarboxylase (AADC), an enzyme that has dopamine decarboxylase activity. It is also unable to cross the blood-brain barrier. As a result, benserazide blocks the conversion of L-DOPA to dopamine by AADC in the peripheral circulatory system. Benserazide is often combined with L-DOPA in patients with Parkinson’s disease.
Chemical Properties
White Crystalline Solid
Uses
Used as antiparkinsonian. A peripheral decarboxylase inhibitor
Uses
Antiparkinsonian;DOPA decarboxylase inhibitor
Uses
Inhibitor of L-aromatic amino acid decarboxylaseBenserazide hydrochloride is used as an antiparkinsonian. It is a peripheral decarboxylase inhibitor. It is used as an inhibitor for aromatic L-aminoacid decarboxylase. Further, it serves as an inhibitor of tyrosine hydroxylase (TH) and Tryptophan hydroxylase (TPH) inhibitor.
Definition
ChEBI: A hydrochloride that is the monohydrochloride salt of benserazide. An aromatic-L-amino-acid decarboxylase inhibitor (DOPA decarboxylase inhibitor) that does not enter the central nervous system, it is used as an adjunct to levodopa in the treatment of park nsonism. By preventing the conversion of levodopa to dopamine in the periphery, it causes an increase in the amount of levodopa reaching the central nervous system and so reduces the required dose. Benserazide hydrochloride has no antiparkinson actions whe given alone.
General Description
Benserazide is a peripheral decarboxylase inhibitor.
Biochem/physiol Actions
Inhibitor of L-aromatic amino acid decarboxylase.
Benserazide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 441)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| QUALITY CONTROL CHEMICALS INC. | (323) 306-3136 | orders@qcchemical.com | United States | 26 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
View Lastest Price from Benserazide hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-13 | Benserazide hydrochloride
14919-77-8
|
US $0.00 / KG | 1KG | 98.5%~101.0%,EP | 800kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | Benserazide hydrochloride
14919-77-8
|
US $46.00 / mg | 99.74% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-03-16 | Benserazide hydrochloride
14919-77-8
|
US $0.00 / KG | 100g | 98%+ | 100kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD |
-
- Benserazide hydrochloride
14919-77-8
- US $0.00 / KG
- 98.5%~101.0%,EP
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Benserazide hydrochloride
14919-77-8
- US $46.00 / mg
- 99.74%
- TargetMol Chemicals Inc.
-
- Benserazide hydrochloride
14919-77-8
- US $0.00 / KG
- 98%+
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
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1of4
RO 4-4602
BENSERAZIDE HYDROCHLORIDE
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DL-SERINE 2-[(2,3,4-TRIHYDROXYPHENYL)METHYL]HYDRAZIDE HCL
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BENSERAZIDE HYDROCHLORIDE EP2000
BENSERAZIDE HYDROCHLORIDE \ PERIPHERAL D
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dl-serine 2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
BENPARIZDE
DL-Serine N2-(2,3,4-trihydroxybenzyl)hydrazide hydrochloride
N'-(DL-Seryl)-N''-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride
N-(DL-Seryl)-N'-(2,3,4-trihydroxybenzyl)hydrazine hydrochloride
Ro 4-4602/001
Serine, 2-(2,3,4-trihydroxybenzyl)hydrazide, monohydrochloride (8CI)
Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, monohydrochloride
2-(2,3,4-TRIHYDROXYBENZYL)HYDRAZIDE
Benserazide hydrochloride(Benserazide HCl)
Benserazide hydrochloride (Serazide)
2-AMino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
N'-(2,3,4-trihydroxybenzyl)-2-amino-3-hydroxypropanehydrazide, hydrochloride(1:1)
(S)-2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
31796-68-6
Benserazide hydrochlo
Madopa (Hoffmann-LaRoche)
NCGC00093698-03
SPECTRUM1500137
Benserazide hydrochioride
2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanohydrazide hydrochloride
(2RS)-2-Amino-3-hydroxy-2′-(2,3,4-trihydroxybenzyl)propanohydrazide hydrochloride
Benserazide hydrochloride, 98%, peripherally acting DOPA decarboxylase inhibitor
Benserazide Hydrochloride >
Benserazide hydrochloride CRS
Benserazide for peak identification CRS
Serine, 2-[(2,3,4-trihydroxyphenyl)methyl]hydrazide, hydrochloride (1:1)
Benserazide hydrochloride USP/EP/BP
Benserazide D3 HydrochlorideQ: What is
Benserazide D3 Hydrochloride Q: What is the CAS Number of
Benserazide D3 Hydrochloride Q: What is the storage condition of
Benserazide D3 Hydrochloride Q: What are the applications of
Benserazide D3 Hydrochloride
Benserazide HydrochlorideQ: What is
Benserazide Hydrochloride Q: What is the CAS Number of
Benserazide Hydrochloride Q: What is the storage condition of
Benserazide Hydrochloride Q: What are the applications of
Benserazide Hydrochloride
BENSERAZIDE HCL
Benserazid hydrochloride
Benserazide Hydrochloride, ≥ 97.0%
2-Amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propanehydrazide hydrochloride
N'-(2,3,4-Trihydroxybenzyl)-(2S)-Benserazide-d3
Benzhydrazine hydrochloride
Benzyserazine hydrochloride
14919-77-8
14064-64-1
4919-77-8
C10H16ClN3O5
BioChemical
Biochemicals and Reagents
Aromatic amino acid decarboxylase, peripheral L-
A to C
Enzymes, Inhibitors, and Substrates