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ChemicalBook >> CAS DataBase List >>(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Structure
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol structure
CAS No.
106083-71-0
Chemical Name:
(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
Synonyms
GW 353162;GW-353162A;BW-306U;Bupropion Morpholinol IMpurity;SS-hydroxybupropion hydrochloride;Bupropion Morpholinol (2S,3S)-Isomer;(2S,3S)-Hydroxybupropion hydrochloride;Bupropion Morpholinol IMpurity (HCl Salt);(2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC);(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol;(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol
CBNumber:
CB42502638
Molecular Formula:
C13H19Cl2NO2
Molecular Weight:
292.2
MDL Number:
MFCD10565921
MOL File:
106083-71-0.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:05
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(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Properties

storage temp. -20°C
solubility DMSO: ≥12mg/mL
form powder
color white to tan
FDA UNII SYD411HZ3S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36
Safety Statements  26
WGK Germany  3
NFPA 704
0
2 0

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H3167 (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) 106083-71-0 5mg $143 2024-03-01 Buy
Sigma-Aldrich H3167 (2S,3S)-Hydroxybupropion hydrochloride ≥98% (HPLC) 106083-71-0 25mg $592 2024-03-01 Buy
American Custom Chemicals Corporation API0004715 GW-353162A 95.00% 106083-71-0 25MG $1029.63 2021-12-16 Buy
ChemScene CS-3815 Radafaxine(hydrochloride) 99.88% 106083-71-0 10mg $192 2021-12-16 Buy
ChemScene CS-3815 Radafaxine(hydrochloride) 99.88% 106083-71-0 5mg $102 2021-12-16 Buy
Product number Packaging Price Buy
H3167 5mg $143 Buy
H3167 25mg $592 Buy
API0004715 25MG $1029.63 Buy
CS-3815 10mg $192 Buy
CS-3815 5mg $102 Buy

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical Properties,Uses,Production

Uses

Antidepressant; antianxiety.

General Description

(2S,3S)-hydroxybupropion is a major metabolite of bupropion.

Biochem/physiol Actions

(2S,3S)-hydroxybupropion is a dopamine transporter (DAT) and norepinephrine transporter (NET) transporters inhibitor and nicotinic acetylcholine receptor (nAChR) family modulator. Hydroxybupropions were reported to contribute to antidepressant and perhaps smoking cessation activities. Both (2S,3S) and (2R,3R) metabolites reverse affective and somatic withdrawal signs in nicotine-dependent mice, but (2S,3S)-hydroxybupropion is more potent. (2S,3S)-hydroxybupropion significantly decreases the development of nicotine reward in mice.

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Xi'an duokai Trading Co., Ltd 029-82283472 15091869467 1055507341@qq.com China 31 58
Syntechem Co.,Ltd info@syntechem.com China 12984 57
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
Standardpharm Co. Ltd. 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Amadis Chemical Company Limited 		58
Xi'an duokai Trading Co., Ltd 58
Syntechem Co.,Ltd 57

106083-71-0((+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol)Related Search:

Bupropion 2-(TERT-BUTYLAMINO)PROPIOPHENONE HYDROCHLORIDE 2-(tert-ButylaMino)-3',5'-chloropropiophenone hydrochloride 1-(3-Chlorophenyl)-2-hydroxy-1-propanone Bupropion Hydrochloride
Bupropion Hydrochloride Related Compound B (15 mg) (2-(tert-butylamino)-3'-bromopropiophenone hydrochloride) 2-(tert-ButylaMino)-3',4'-chloropropiophenone hydrochloride Bupropion Hydrochloride Related Compound A (15 mg) (2-(tert-butylamino)-4'-chloropropiophenone hydrochloride) 2-(tert-ButylaMino)-2'-chloropropiophenone Hydrochloride (R,R)-Hydroxy Bupropion

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(+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride (2S,3S)-Hydroxybupropion hydrochloride GW 353162 SS-hydroxybupropion hydrochloride (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Bupropion Morpholinol IMpurity Bupropion Morpholinol IMpurity (HCl Salt) Bupropion Morpholinol (2S,3S)-Isomer GW-353162A;BW-306U (2S,3S)-Hydroxybupropion hydrochloride >=98% (HPLC) (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol 106083-71-0