ChemicalBook >> CAS DataBase List >>4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

CAS No.
131666-45-0
Chemical Name:
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester
Synonyms
Flumazenil EP Impurity B;FlumazenilEPImpurityB-d3;Flumazenil impurity B CRS;Flumazenil impurity B (EP);Defluoro 8-Hydroxy Flumazenil;Flumazenil USP Related Compound B;Defluoro 8-Hydroxy FluMazenil (IMpurity);Flumazenil Impurity 2(Flumazenil EP Impurity B);4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-d...;Ethyl8-hydroxy-5-methyl-6-oxo-4H-imidazol1,5-A1,4benzodiazepine-3-carboxylate
CBNumber:
CB42505664
Molecular Formula:
C15H15N3O4
Molecular Weight:
301.3
MDL Number:
MOL File:
131666-45-0.mol
Last updated:2023-04-23 13:52:06

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Properties

Boiling point 588.6±50.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
pka 8.54±0.20(Predicted)
FDA UNII YXG5MZU3SQ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P313-P337+P313-P362-P403+P233-P405-P501

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000335 Flumazenil impurity B European Pharmacopoeia (EP) Reference Standard 131666-45-0 y0000335 $153 2024-03-01 Buy
Sigma-Aldrich 1273820 Flumazenil impurity B 131666-45-0 20mg $1780 2024-03-01 Buy
TRC D228740 Defluoro8-HydroxyFlumazenil(Impurity) 131666-45-0 2.5mg $160 2021-12-16 Buy
AK Scientific 6319DT Ethyl8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate 131666-45-0 5mg $329 2021-12-16 Buy
Product number Packaging Price Buy
Y0000335 y0000335 $153 Buy
1273820 20mg $1780 Buy
D228740 2.5mg $160 Buy
6319DT 5mg $329 Buy

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Chemical Properties,Uses,Production

Uses

Defluoro 8-hydroxy Flumazenil is an impurity of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Defluoro 8-Hydroxy FluMazenil (IMpurity) Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate Flumazenil EP Impurity B Flumazenil impurity B (EP) Flumazenil Impurity 2(Flumazenil EP Impurity B) Flumazenil impurity B CRS Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-d... Defluoro 8-Hydroxy Flumazenil FlumazenilEPImpurityB-d3 Flumazenil USP Related Compound B Ethyl8-hydroxy-5-methyl-6-oxo-4H-imidazol1,5-A1,4benzodiazepine-3-carboxylate 131666-45-0