Guvacoline Hydrobromide
- CAS No.
- 17210-51-4
- Chemical Name:
- Guvacoline Hydrobromide
- Synonyms
- 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Methyl Ester HydrobroMide;1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, methyl ester, monohydrobromide
- CBNumber:
- CB42509354
- Molecular Formula:
- C7H12BrNO2
- Molecular Weight:
- 222.07968
- MDL Number:
- MFCD02683335
- MOL File:
- 17210-51-4.mol
Guvacoline Hydrobromide price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17190 | Guvacoline (hydrobromide) ≥98% | 17210-51-4 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 17190 | Guvacoline (hydrobromide) ≥98% | 17210-51-4 | 5mg | $161 | 2024-03-01 | Buy |
| Cayman Chemical | 17190 | Guvacoline (hydrobromide) ≥98% | 17210-51-4 | 10mg | $299 | 2024-03-01 | Buy |
| TRC | G876500 | GuvacolineHydrobromide | 17210-51-4 | 50mg | $790 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0901111 | GUVACOLINE HYDROBROMIDE 95.00% | 17210-51-4 | 100MG | $1732.5 | 2021-12-16 | Buy |
Guvacoline Hydrobromide Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Uses
A muscarinic receptor used as nootropic agent.
Biological Activity
guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. guvacoline can function as a full agonist of atrial and ileal muscarinic receptors.in vitro: in human buccal epithelial cells, guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the ic50 value of 2.1 mm. besides, guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mm guvacoline caused 25% decrease) and increase the number of single strand breaks [1].
target
atrial and ileal muscarinic receptors
IC 50
2.1 mm for growth inhibition of human buccal epithelial cells
References
[1] k. sundqvist, y. liu, j. nair, et al. cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells. cancer research 49(19), 5294-5298 (1989).
Guvacoline Hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChengDu Yijierui Biotechnology CO., Ltd | 182-24028459 18224018291 | 3004072879@qq.com | China | 1224 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 18018 | 56 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 56068 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| ChengDu YiRui Bio-Technology CO., LTD | 182-24028459 18224018291 | 3004072879@qq.com | China | 1203 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |