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ChemicalBook >> CAS DataBase List >>6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Structure
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate structure
CAS No.
288628-05-7
Chemical Name:
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate
Synonyms
STX 64;ST-64667;BN 83495;STX64667;STX 64667;Irosustat;Irosustat(STX64);COUMATE. Irosustat.;DSLPMJSGSBLWRE-UHFFFAOYSA-N;STX64 - BN83495 | Irosustat | 667 Coumate
CBNumber:
CB42597564
Molecular Formula:
C14H15NO5S
Molecular Weight:
309.34
MDL Number:
MFCD12912443
MOL File:
288628-05-7.mol
MSDS File:
SDS
Last updated:2024-11-19 23:02:33
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6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Properties

Melting point 170.1-173.4 °C
Boiling point 544.1±60.0 °C(Predicted)
Density 1.48±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
form white powder
pka 8.26±0.70(Predicted)
color White to off-white
FDA UNII 366037O6O7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany  3

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S1950 STX64 ≥98% (HPLC) 288628-05-7 5mg $211 2024-03-01 Buy
Sigma-Aldrich S1950 STX64 ≥98% (HPLC) 288628-05-7 25mg $662 2024-03-01 Buy
TRC S687208 STX64 288628-05-7 2.5mg $275 2021-12-16 Buy
Axon Medchem Axon2892 STX64-BN83495|Irosustat|667Coumate 99% 288628-05-7 5mg $99 2021-12-16 Buy
American Custom Chemicals Corporation API0005149 BN-83495 95.00% 288628-05-7 5MG $728 2021-12-16 Buy
Product number Packaging Price Buy
S1950 5mg $211 Buy
S1950 25mg $662 Buy
S687208 2.5mg $275 Buy
Axon2892 5mg $99 Buy
API0005149 5MG $728 Buy

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Chemical Properties,Uses,Production

Uses

STX64 is a potent, irreversible inhibitor of steroid sulfatase.

Biochem/physiol Actions

STX64 is a potent, irreversible inhibitor of steroid sulfatase. Inhibition of steroid sulfatase (STS), the enzyme responsible for the hydrolysis of steroid sulfates, represents a potential novel treatment for postmenopausal women with hormone-dependent breast cancer. Estrone and DHEA are formed by this sulfatase pathway and can be converted to steroids (estradiol and androstenediol, respectively), which have potent estrogenic properties. STX64 (667 coumate) is a potent tricylic coumarin-based sulfamate that irreversibly inhibits STS activity (IC50 = 8 nM in a placental microsomal assay system). Estrone sulfamate (EMATE) is also a potent STS inhibitor, but has estrogenic activity.

storage

Store at -20°C

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Preparation Products And Raw materials

Raw materials

Preparation Products

6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30240 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9639 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38632 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43340 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
SembCorp Shenzhenshibai a Biotechnology Co., Ltd 13412890622 China 23 55
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
Finetech Industry Limited 		58
Labnetwork lnc. 		58
InvivoChem 		58
TargetMol Chemicals Inc. 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
SembCorp Shenzhenshibai a Biotechnology Co., Ltd 55

View Lastest Price from 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Irosustat pictures 2024-11-19 Irosustat
288628-05-7
 US $47.00-173.00 / mg 98.76% 10g TargetMol Chemicals Inc.
  • Irosustat pictures
  • Irosustat
    288628-05-7
  • US $47.00-173.00 / mg
  • 98.76%
  • TargetMol Chemicals Inc.
6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c][1]benzopyran-3-yl sulfaMate BN 83495 Irosustat STX 64 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate DSLPMJSGSBLWRE-UHFFFAOYSA-N STX64 - BN83495 | Irosustat | 667 Coumate COUMATE. Irosustat. ST-64667 STX 64667 STX64; STX-64; STX 64; BN83495; BN-83495; BN 83495; STX 64667; STX64667; ST-64667; COUMATE. IROSUSTAT. STX64667 Irosustat(STX64) (6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-3-yl) sulfamate Sulfamic acid, 6,7,8,9,10,11-hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl ester BN 83495,Irosustat,Inhibitor,STX-64,STX 64,inhibit,BN-83495 288628-05-7