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(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)

CAS No.
909725-64-0
Chemical Name:
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
Synonyms
W140;W140 (TFA);(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt);(S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140
CBNumber:
CB42720643
Molecular Formula:
C18H28F3N2O6P
Molecular Weight:
456.4
MDL Number:
MOL File:
909725-64-0.mol
Last updated:2023-05-21 10:59:17

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Properties

storage temp. Store at -20°C
solubility Ethanol: 0.15 mg/ml
form A crystalline solid

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10009110 W140 (trifluoroacetate salt) ≥95% 909725-64-0 500μg $78 2024-03-01 Buy
Cayman Chemical 10009110 W140 (trifluoroacetate salt) ≥95% 909725-64-0 1mg $146 2024-03-01 Buy
Cayman Chemical 10009110 W140 (trifluoroacetate salt) ≥95% 909725-64-0 5mg $614 2024-03-01 Buy
Cayman Chemical 10009110 W140 (trifluoroacetate salt) ≥95% 909725-64-0 10mg $1071 2024-03-01 Buy
AK Scientific 3145EL [(3S)-3-Amino-4-(3-hexylanilino)-4-oxobutyl]phosphonicacid;2,2,2-trifluoroaceticacid 909725-64-0 1mg $262 2021-12-16 Buy
Product number Packaging Price Buy
10009110 500μg $78 Buy
10009110 1mg $146 Buy
10009110 5mg $614 Buy
10009110 10mg $1071 Buy
3145EL 1mg $262 Buy

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Chemical Properties,Uses,Production

Description

W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 .1 It only weakly binds to S1P1 (Ki = 4.6 μM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.1,2

References

1. Sanna, M.G., Wang, S.K., Gonzalez-Cabrera, P.J., et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo Nat. Chem. Biol. 2(8),434-441(2006).
2. Li, C., Chi, X.X., Xie, W., et al. Sphingosine 1-phosphate receptor 2 antagonist JTE-013 increases the excitability of sensory neurons independently of the receptor J. Neurophysiol. 108(5),1473-1483(2012).

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) Suppliers

Global( 18)Suppliers
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Creative Enzymes
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Aladdin Scientific
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Codow Chemical Co.,Ltd. 18620099427 amy@howeipharm.com China 17687 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9806 58
Chengdu Dianchun Technology Co., Ltd 400-1166-196 18502815961 cdhxsj@163.com China 14603 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8140 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725 malulu@leyan.com China 39988 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12065 58
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt) (S)-3-AMINO-4-(3-HEXYLPHENYLAMINO)-4-OXOBUTYLPHOSPHONIC ACID (TFA SALT);W140 W140 W140 (TFA) 909725-64-0