ChemicalBook >> CAS DataBase List >>USP7-IN-1
USP7-IN-1
- CAS No.
- 1381291-36-6
- Chemical Name:
- USP7-IN-1
- Synonyms
- USP7i-1;USP7-IN-1;USP7 inhibitor 1;Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase;4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
- CBNumber:
- CB42729378
- Molecular Formula:
- C23H24ClN3O3
- Molecular Weight:
- 425.91
- MDL Number:
- MOL File:
- 1381291-36-6.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:08
USP7-IN-1 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-3515 | USP7-IN-1 98.92% | 1381291-36-6 | 5mg | $420 | 2021-12-16 | Buy |
ChemScene | CS-3515 | USP7-IN-1 98.92% | 1381291-36-6 | 10mg | $600 | 2021-12-16 | Buy |
ChemScene | CS-3515 | USP7-IN-1 98.92% | 1381291-36-6 | 50mg | $1800 | 2021-12-16 | Buy |
ChemScene | CS-3515 | USP7-IN-1 98.92% | 1381291-36-6 | 100mg | $2520 | 2021-12-16 | Buy |
Crysdot | CD31003679 | USP7-IN-1 98+% | 1381291-36-6 | 5mg | $243 | 2021-12-16 | Buy |
USP7-IN-1 Chemical Properties,Uses,Production
Description
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. IC50: 77 μM (USP7)[1]
USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM[1].
References
[1]. SELECTIVE AND REVERSIBLE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 7. WO 2013030218 A1
![1426340-66-0](/CAS/20210305/GIF/1000210-73-0.gif)
![501-52-0](/CAS/GIF/501-52-0.gif)
![1381291-36-6](/CAS/20150408/GIF/1381291-36-6.gif)
Synthesis of USP7-IN-1 from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy- and 3-Phenylpropionic acid
USP7-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
USP7-IN-1 Suppliers
Global( 29)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
LETOPHARM LIMITED | +86-21-5821 5861 | sales@letopharm.com | China | 2384 | 58 |
Birdo (Shanghai) Medical Technology Co., Ltd. | 021-58099077 | sales@birdochem.com | China | 185 | 55 |
Shanghai Beckham Medical Technology Co., Ltd | 021-13816613772 13816613772 | huahero21@sina.com | China | 384 | 55 |
Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3868 | 58 |
USP7-IN-1
4(3H)-Quinazolinone, 7-chloro-3-[[4-hydroxy-1-(1-oxo-3-phenylpropyl)-4-piperidinyl]methyl]-
USP7i-1
USP7 inhibitor 1
Inhibitor,inhibit,USP-7-IN-1,USP7IN1,USP7 IN 1,DUBs,Deubiquitinase
1381291-36-6