ChemicalBook >> CAS DataBase List >>HJC-0123
HJC-0123
- CAS No.
- 1430420-02-2
- Chemical Name:
- HJC-0123
- Synonyms
- HJC-0123;4-Quinolinecarboxamide, N-(1,1-dioxidobenzo[b]thien-6-yl)-2-phenyl-
- CBNumber:
- CB42731067
- Molecular Formula:
- C24H16N2O3S
- Molecular Weight:
- 412.46
- MDL Number:
- MOL File:
- 1430420-02-2.mol
Last updated:2024-10-23 13:36:13
HJC-0123 Chemical Properties,Uses,Production
Description
Downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values. Furthermore, HJC-0123 significantly suppressed estrogen receptor (ER)-negative breast cancer MDA-MB-231 xenograft tumor growth in vivo (p.o.), indicating its great potential as an efficacious and orally bioavailable drug candidate for human cancer therapy.
HJC-0123 Preparation Products And Raw materials
Raw materials
Preparation Products
HJC-0123 Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19711 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
HJC-0123
4-Quinolinecarboxamide, N-(1,1-dioxidobenzo[b]thien-6-yl)-2-phenyl-
1430420-02-2