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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate structure

CAS No.: 82692-93-1

Chemical Name:: Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate

Synonyms: TOOS;Trinder Reagent;TOOS, SODIUM SALT;TOOS extrapure, 98%;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE;N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT;Peroxidase/Hydrogen Peroxide Detection , Colorimetry;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO;N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT;SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE

CBNumber:: CB4279813

Molecular Formula:: C12H20NNaO4S

Molecular Weight:: 297.34

MDL Number:: MFCD00040641

MOL File:: 82692-93-1.mol

MSDS File:: SDS

Last updated:2025-04-18 09:52:20

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Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Properties

storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Solid
color	White to Almost white
BRN	5689521
InChI	InChI=1S/C12H19NO4S.Na.H/c1-3-13(8-12(14)9-18(15,16)17)11-6-4-5-10(2)7-11;;/h4-7,12,14H,3,8-9H2,1-2H3,(H,15,16,17);;
InChIKey	IRQRBVOQGUPTLG-UHFFFAOYSA-M
SMILES	N(C1C=CC=C(C)C=1)(CC)CC(O)CS(O)(=O)=O.[NaH]
CAS DataBase Reference	82692-93-1(CAS DataBase Reference)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

HS Code

29214200

NFPA 704

	0
0		0

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E8631	3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt for enzymic, spectrophotometric det. of H	82692-93-1	1g	$169	2024-03-01	Buy
Sigma-Aldrich	04340	3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt for enzymic, spectrophotometric determination of H	82692-93-1	500mg	$99.8	2024-03-01	Buy
TCI Chemical	S0805	Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate >98.0%(HPLC)	82692-93-1	1g	$36	2024-03-01	Buy
TCI Chemical	S0805	Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate >98.0%(HPLC)	82692-93-1	5g	$104	2024-03-01	Buy
Sigma-Aldrich	E8631	3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt for enzymic, spectrophotometric det. of H	82692-93-1	5g	$627	2024-03-01	Buy

Product number	Packaging	Price	Buy
E8631	1g	$169	Buy
04340	500mg	$99.8	Buy
S0805	1g	$36	Buy
S0805	5g	$104	Buy
E8631	5g	$627	Buy

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Chemical Properties,Uses,Production

Description

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used in the enzymatic photometric determination of hydrogen peroxide. This compound is a widely studied small molecule inhibitor in scientific research. Originally synthesized in the early 1980s, it has since found extensive use in various investigations into cellular processes. It has its inhibition of the Na+/H+ exchanger (NHE), which is a membrane protein crucial for regulating intracellular pH. Additionally, EIPA has shown its potential as an inhibitor of TRPV channels, which play a role in pain sensation and thermoregulation. Another significant finding indicates Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate′s inhibition of the Na+/Ca2+ exchanger (NCX), responsible for regulating intracellular calcium levels.

Chemical Properties

White crystalline powder

Uses

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1].

References

[1] Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647. DOI:10.1016/j.talanta.2021.122647

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate synthesis

Synthesis of Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate from Sodium 3-Chloro-2-hydroxypropanesulfonate and N-Ethyl-3-methylaniline

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Preparation Products And Raw materials

Raw materials

Sodium 3-Chloro-2-hydroxypropanesulfonate N-Ethyl-3-methylaniline

Preparation Products

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Suppliers

Global( 277)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Xindesheng Material Technology Co., Ltd.	+8618971041571	vickyzhao@whdschem.com	China	174	58
Suzhou BEC Biological Technology Co., Ltd.	+undefined13771885869	all@bek.com.cn	China	62	58
Hebei Mujin Biotechnology Co.,Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12809	58
Hebei Yanxi Chemical Co., Ltd.	+8617531153977	allison@yan-xi.com	China	5854	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18137	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19805	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58

Supplier	Advantage
Hubei Xindesheng Material Technology Co., Ltd.	58
Suzhou BEC Biological Technology Co., Ltd.	58
Hebei Mujin Biotechnology Co.,Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

Application of Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used for the determination of hydrogen....
Nov 3，2022

View Lastest Price from Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-25	Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1	US $0.00 / KG	1KG	99%	3500kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2025-04-15	Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-03-21	Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate 82692-93-1	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mujin Biotechnology Co.,Ltd

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
US $0.00 / KG
99%
WUHAN FORTUNA CHEMICAL CO., LTD

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate
82692-93-1
US $0.00 / KG
99%
Hebei Mujin Biotechnology Co.,Ltd

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Spectrum

Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate(82692-93-1)¹HNMR

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3-(N-ETHYL-M-TOLUIDINO)-2-HYDROXYPROPANE-SULFONIC ACID SODIUM SALT 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUM SALT 3-(n-ethyl-3-methylanilino)-2-hydroxypropansulf.acidso-salt 3-[ethyl(3-methylphenyl)amino]-2-hydroxy-1-propanesulfonicacimonosodiums N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE SODIUM SALT N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-TOLUIDINE SODIUM SALT TOOS TOOS, SODIUM SALT SodiuM 3-[Ethyl(M-tolyl)aMino]-2-hydroxy-1-propanesulfonate 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonic Acid Sodium Salt 3-(N-ethyl-Methylanilino)-2-hydroxy Propane sulfonic acid, SodiuM Salt 3-(Ethyl(M-tolyl)aMino)-2-hydroxypropane-1-sulfonic acid, sodiuM salt Sodium 3-(ethyl(m-tolyl)amino)-2-hydroxypropane-1-sulfonate 3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Sodium N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine TOOS SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE SODIUM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline sodium salt Peroxidase/Hydrogen Peroxide Detection , Colorimetry Trinder Reagent SODIUM 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONATE TOOS N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt (N=1) TOOS (3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUMSALT) N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE,SODIUMSALT(TOOS) N-Ethyl-N-sulphohydroxypropyl-m-toluidine, sodium salt >98% N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate, Sodium N-ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine, TOOS, N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt, 3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt TOOS (3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline sodium 3-(N-ethyl-Methylanilino)-2-hydroxy propane sulfonic acid, SodiuM N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-*M-T OLUIDINE SO N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-METHYLANILINE N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline,sodiumsalt,dihydrate 3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANSULF.ACIDSODIUMSALT 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt ,99% 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt,3-(N-Ethyl-m-toluidino)-2-hydroxypropanesulfonic acid sodium salt, N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-m-toluidine sodium salt, So N-ethyl-N-(2-hydroxy-3-sulfonatopropyl)-3-methylaniline sodium salt Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfote Sodium 3-[Ethyl(m-tolyl)amino]-2-hydroxy-1-propanesulfonate Hydrate> N-Ethyl-N-sulfohydroxypropyl-m-toluidine sodium salt (TOOS) 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt monohydrate TOOS extrapure, 98% 3-(N-ethyl-methylanilino)-2-hydroxy Propane sulfonic acid, Sodium Salt(TOOS) 3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodium salt 82692-93-1 C12H18NaO4S C12H20NNaO5S C12H18NNaO4SxH2O Biochemicals and Reagents Analytical Standards Alphabetic Analytical Chromatography Product Catalog BioChemical Substrates by Enzyme Enzyme Substrates