ChemicalBook >> CAS DataBase List >>Budralazine

Budralazine

CAS No.
36798-79-5
Chemical Name:
Budralazine
Synonyms
PTLZ;DJ-1461;Butrazine;Buterazine;BUDRALAZINE;1,2H-PHTHALAZONE;DIHYDROOXOPHTHALAZINE;Budralazine USP/EP/BP;1,2-DIHYDROPHTHALAZIN-1-ONE;1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE
CBNumber:
CB4282099
Molecular Formula:
C14H16N4
Molecular Weight:
240.3
MDL Number:
MFCD00869279
MOL File:
36798-79-5.mol
Last updated:2024-10-23 13:36:13

Budralazine Properties

Melting point 183-185 °C(lit.)
Boiling point 373.02°C (rough estimate)
Density 1.1506 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Amber Vial, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 9.54±0.70(Predicted)
color Light Yellow to Yellow
Stability Light Sensitive
CAS DataBase Reference 36798-79-5(CAS DataBase Reference)
FDA UNII S0177QHV2B

SAFETY

Risk and Safety Statements

Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  TH9185000
Toxicity LD50 in mice, rats (mg/kg): 1820, 620 orally; 4020, 3570 i.p. (Onodera)

Budralazine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B689515 Budralazine 36798-79-5 50mg $185 2021-12-16 Buy
American Custom Chemicals Corporation API0001776 BUDRALAZINE 95.00% 36798-79-5 50MG $329.7 2021-12-16 Buy
Medical Isotopes, Inc. 18537 Budralazine 36798-79-5 25mg $1500 2021-12-16 Buy
American Custom Chemicals Corporation API0001776 BUDRALAZINE 95.00% 36798-79-5 500MG $1963.5 2021-12-16 Buy
Product number Packaging Price Buy
B689515 50mg $185 Buy
API0001776 50MG $329.7 Buy
18537 25mg $1500 Buy
API0001776 500MG $1963.5 Buy

Budralazine Chemical Properties,Uses,Production

Description

Budralazine is an antihypertensive agent which is somewhat less potent than structurally related hydralazine, and reportedly produces less tachycardia.

Originator

Daiichi (Japan)

Uses

Budralazine a new antihypertensive agent. Budralazine is a direct-acting vasodilator.

Definition

ChEBI: Budralazine is a member of phthalazines.

Manufacturing Process

A mixture of 2.0 g of 1-hydrazinophthalazine hydrochloride, 1.1 g of mesityl oxide (isoproplyideneacetone) and 100 ml of ethanol, was refluxed for 3 hours. The reaction mixture was concentrated in vacuo and the residue was dissolved in water. The water solution was neutralized with sodium bicarbonate, salted out and the product was extracted with benzene. The benzene layer was passed through a comparatively short column of alumina and the solvent was removed. The residue was crystallized from ether to give 0.7 g of 1-(1,3-dimethyl-2-butenylidene) hydrazinophthalazine, melting point 131°-132°C.

brand name

BUTERAZINE

Therapeutic Function

Antihypertensive

Budralazine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 61)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32165 58
Hubei Ipure Biology Co., Ltd
+8613367258412 ada@ipurechemical.com China 10319 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 7724 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19885 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57412 58

View Lastest Price from Budralazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Budralazine pictures 2024-10-24 Budralazine
36798-79-5
US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
Budralazine pictures 2020-05-10 Budralazine
36798-79-5
US $0.00-0.00 / Kg 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
  • Budralazine pictures
  • Budralazine
    36798-79-5
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
  • Budralazine pictures
  • Budralazine
    36798-79-5
  • US $0.00-0.00 / Kg
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd
PTLZ 1-(2-(1,3-DIMETHYL-2-BUTENYLIDENE)HYDRAZINO)PHTHALAZINE 1,2-DIHYDROPHTHALAZIN-1-ONE 1,2H-PHTHALAZONE 1,3-DIHYDRO-4-KETO-2 3-BENZODIAZINE DIHYDROOXOPHTHALAZINE BUDRALAZINE 1-[2-(1,3-Dimethyl-2-buten-1-ylidene)hydrazino]phthalazine 4-Methyl-3-penten-2-one (phthalazin-1-yl)hydrazone Buterazine DJ-1461 1(2H)-Phthalazinone (1,3-DiMethyl-2-butenylidene)hydrazone 4-Methyl-3-Penten-2-one 2-(1-phthalazinyl)hydrazone Budralazine USP/EP/BP 3-Penten-2-one, 4-methyl-, 2-(1-phthalazinyl)hydrazone Butrazine 36798-79-5 Pyridazines Heterocyclic Building Blocks Building Blocks