Anti-Translocated in liposarcoma protein
- CAS No.
- Chemical Name:
- Anti-Translocated in liposarcoma protein
- Synonyms
- FUS;ALS6;FUS1;HNRNPP2;Anti-POMp75;Anti-Oncogene TLS;Anti-Oncogene FUS;Anti-RNA-binding protein FUS;Anti-75 kDa DNA-pairing protein;Anti-FUS antibody produced in rabbit
- CBNumber:
- CB42879271
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-Translocated in liposarcoma protein price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | HPA008784 | Anti-FUS antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $282 | 2023-06-20 | Buy | |
Sigma-Aldrich | HPA008784 | Anti-FUS antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2023-06-20 | Buy | |
Usbiological | 396391 | FUS | 48Tests | $588 | 2021-12-16 | Buy | |
Biorbyt Ltd | orb531794 | FUS | 10μg | $863.6 | 2021-12-16 | Buy |
Anti-Translocated in liposarcoma protein Chemical Properties,Uses,Production
Uses
Anti-FUS antibody produced in rabbit has been used in:
- immunohistochemistry
- immunoblotting
- immunofluorescence
Uses
Anti-FUS antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .
Uses
Anti-FUS/TLS polyclonal antibody is used to tag FUsed in sarcoma/translocated in LipoSarcoma proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of FUsed in sarcoma/translocated in LipoSarcoma proteins in transcription and mRNA processing and amyotrophic lateral sclerosis, ALS6
General Description
Fused in sarcoma (FUS); translocated in LipoSarcoma (TLS) is a component of a fusion pro-oncogene resulting from a chromosomal translocation seen in liposarcomas. FUS/TLS belongs to a sub-family of RNA binding proteins that interacts with RNA, ssDNA, and dsDNA. FUS/TLS is involved in unique functions in mRNA processing and transport, transcriptional regulation and maintenance of genomic stability. FUsed in sarcoma (FUS); Translocated in LipoSarcoma (TLS) is a multifunctional protein implicated in a wide range of cellular processes, including transcription and mRNA processing, as well as in both cancer and neurological disease. Mutations in the fused in sarcoma (FUS) gene are linked to a form of familial amyotrophic lateral sclerosis (ALS), ALS6.
Biochem/physiol Actions
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq]
Anti-Translocated in liposarcoma protein Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-Translocated in liposarcoma protein Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
AntibodySystem | 17762345272 18162686757 | biolab-reagents@atagenix.com | China | 9817 | 58 |
ACROBiosystems | 18514007688 | jiaxin.zhao@acrobiosystems.com | China | 976 | 58 |
Supplier | Advantage |
---|---|
Sigma-Aldrich | 80 |
AntibodySystem | 58 |
ACROBiosystems | 58 |