Anti-IFN-alpha-REC
- CAS No.
- Chemical Name:
- Anti-IFN-alpha-REC
- Synonyms
- Anti-IFN-alpha-REC;Anti-IFNAR1 antibody produced in rabbit;Anti-Interferon-alpha/beta receptor alpha chain precursor
- CBNumber:
- CB42884880
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Anti-IFN-alpha-REC price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | HPA018015 | Anti-IFNAR1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 25μL | $294 | 2024-03-01 | Buy | |
Sigma-Aldrich | HPA018015 | Anti-IFNAR1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $547 | 2024-03-01 | Buy |
Anti-IFN-alpha-REC Chemical Properties,Uses,Production
Uses
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General Description
Interferon-α/β receptor α chain precursor (IFNAR1) is part of a heterodimeric receptor and contains an intracellular motif with a unique peptide sequence. The gene encoding it is localized on chromosome 21.
Biochem/physiol Actions
Interferon-α/β receptor α chain precursor (IFNAR1) acts as a receptor for the pro-inflammatory cytokine interferon α (IFN-α) and is involved in immune processes during malaria infection. When IFN-α binds to IFNAR1, Janus kinases (JAKs) are activated. They then phosphorylate signal transducer and activator of transcription 1 (STAT1) and STAT2. This complex then enters the nucleus and activates antiviral gene transcription. Single-nucleotide polymorphisms in IFNAR1 have shown to be risk factors for malaria. IFNAR1 is down regulated in Hepatitis C Virus (HCV)-linked chronic liver diseases.
Anti-IFN-alpha-REC Preparation Products And Raw materials
Raw materials
Preparation Products
Anti-IFN-alpha-REC Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 292394 | 58 |
Supplier | Advantage |
---|---|
Merck KGaA | 58 |