HUMAN SDF1A (67AA) (CXCL12)
- CAS No.
- Chemical Name:
- HUMAN SDF1A (67AA) (CXCL12)
- Synonyms
- SDF-1;CXCL12;SDF-1a;HUMAN SDF-1A;hIRH;SCYB12;SDF-1b;PBSF, HUMAN;SDF-1 ALPHA;RHSDF-1ALPHA
- CBNumber:
- CB4296090
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01324714
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| FDA UNII | CPN2JYW64D |
HUMAN SDF1A (67AA) (CXCL12) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SRP4391 | SDF-1beta (CXCL12) from mouse recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) | 10μG | $362 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SRP3276 | SDF-1 ALPHA human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC) | 10μG | $413 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1412233 | ANTI-CXCL12 antibody produced in mouse clone 2B1, purified immunoglobulin, buffered aqueous solution | 100μG | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1412070 | ANTI-CXCL12 antibody produced in mouse clone 4D8, purified immunoglobulin, buffered aqueous solution | 100μG | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SRP4388 | SDF-1alpha (CXCL12) from mouse recombinant, expressed in E. coli, ≥99% (SDS-PAGE), ≥99% (HPLC) | 10μG | $339 | 2023-06-20 | Buy |
HUMAN SDF1A (67AA) (CXCL12) Chemical Properties,Uses,Production
Uses
SDF-1α (stromal cell-derived factor 1 α) human?has been used in the chemotaxis assay of neural crest cells (NCCs) and as a component of Dulbecco′s modified Eagle′s medium (DMEM) in migration assay of human mesenchymal stem cells (hMSCs).
General Description
SDF-1α (stromal cell-derived factor 1 α) and β are stromal derived CXC chemokines, and signal through the CXCR4 (C-X-C motif chemokine receptor). SDF1α is an isoform of CXCL12 (C-X-C motif chemokine 12, also referred to as SDF-1). The gene is mapped to human chromosome 10q11. Recombinant human SDF-1a is an 8.0kDa protein containing 68 amino acid residues.
Biochem/physiol Actions
SDF-1α (stromal cell-derived factor 1 α) and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. SDF-1 is mainly expressed in the inflamed and failing myocardium. It is involved in inflammation, proliferation, tumorigenicity and metastasis. The SDF-1 proteins exert HIV (human immunodeficiency virus) suppressive activity in cells expressing the CXCR4 (C-X-C motif chemokine receptor 4). It is upregulated in breast carcinoma, ovarian carcinoma and papillary thyroid carcinoma. It enhances angiogenesis in the ischemic tissue. SDF1 is also involved in neuroprotection after ischemic stroke with the help of CXCR4.
HUMAN SDF1A (67AA) (CXCL12) Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN SDF1A (67AA) (CXCL12) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10069 | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 7762 | 58 |
| Shanghai Huzhen Industrial Co., LTD | 021-60345367 13916550749 | sales@shzbio.com | China | 9965 | 58 |
| AntibodySystem | 027-65279366 18162686757 | biolab-reagents@atagenix.com | China | 10622 | 58 |
| ACROBiosystems | 18514007688 | jiaxin.zhao@acrobiosystems.com | China | 947 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 58 |
| Shanghai Yaji Biological Technology Co., Ltd. | 58 |
| Shanghai Huzhen Industrial Co., LTD | 58 |
| AntibodySystem | 58 |
| ACROBiosystems | 58 |
| United States Biological | 58 |