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Sucrose octaacetate

CAS No.
126-14-7
Chemical Name:
Sucrose octaacetate
Synonyms
Soa;FEMA 3038;SUCROSE OCTACETATE;Octa D;aacetate;204-772-1;bitter taste;OCTAACETYLSUCROSE;Sucrose octa actate;Sucrose octaacetate
CBNumber:
CB4296191
Molecular Formula:
C28H38O19
Molecular Weight:
678.59
MDL Number:
MFCD00006623
MOL File:
126-14-7.mol
Last updated:2024-10-31 13:32:20

Sucrose octaacetate Properties

Melting point 82-85 °C(lit.)
Boiling point 260 °C(lit.)
alpha D25.4 +58.5° (c = 2.56 in abs alcohol)
Density 1.28
FEMA 3038 | SUCROSE OCTAACETATE
refractive index 60 ° (C=2, EtOH)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form Powder
color White to creamy white
Odor odorless
Odor Type odorless
optical activity [α]22/D +58.8°, c = 2.5 in ethanol
Water Solubility SLIGHTLY SOLUBLE
Merck 14,8881
BRN 79290
InChIKey ZIJKGAXBCRWEOL-SAXBRCJISA-N
LogP 3.19
CAS DataBase Reference 126-14-7(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) SUCROSE OCTAACETATE
FDA 21 CFR 172.515; 175.105
EWG's Food Scores 1
FDA UNII 07V591057T
NIST Chemistry Reference Sucrose, octaacetate(126-14-7)
EPA Substance Registry System Sucrose octaacetate (126-14-7)

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-37/39-26
WGK Germany  2
RTECS  WN6620000
3
HS Code  29400090
Toxicity LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg

Sucrose octaacetate price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 1kg $105 2024-03-01 Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 10Kg $666 2024-03-01 Buy
Sigma-Aldrich W303801 Sucrose octaacetate ≥97%, FG 126-14-7 25kg $1200 2024-03-01 Buy
Sigma-Aldrich 8.22144 D-(+)-Saccharose octaacetate for synthesis 126-14-7 250g $67.5 2024-03-01 Buy
Sigma-Aldrich 252603 D-(+)-Sucrose octaacetate 98% 126-14-7 1kg $129 2024-03-01 Buy
Product number Packaging Price Buy
W303801 1kg $105 Buy
W303801 10Kg $666 Buy
W303801 25kg $1200 Buy
8.22144 250g $67.5 Buy
252603 1kg $129 Buy

Sucrose octaacetate Chemical Properties,Uses,Production

Chemical Properties

white to creamy white powder

Chemical Properties

Sucrose octaacetate is odorless with an intensly bitter flavor influenced by food acids

Chemical Properties

Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.

Uses

LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide

Uses

Adhesive; impregnating and insulating papers; in lacquers and plastics; as a denaturant for alcohol.

Uses

Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.

Definition

ChEBI: Sucrose octaacetate is a glycoside.

Production Methods

Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.

Preparation

May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.

Pharmaceutical Applications

Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.

Safety Profile

Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.

Safety

Sucrose octaacetate is generally regarded as safe. It is considered slightly hazardous in cases of skin contact (irritant), ingestion, or inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg

storage

Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.

Purification Methods

After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]

Regulatory Status

GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.

Sucrose octaacetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 378)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhejiang Synose Tech Co., Ltd
579-82270620 expo@synose.com CHINA 218 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5893 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2472 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021 lisa@kingfinertech.com China 2990 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@sdzhonghuimaterial.com China 983 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3002 58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.
+8615373025980 clara@hbshengyang.com China 874 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046 sales01@watsonbiotech.cn China 5821 58
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
+86-15350851019 +86-15383190639 admin@86-ss.com China 1000 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18644 58

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View Lastest Price from Sucrose octaacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sucrose octaacetate pictures 2024-11-04 Sucrose octaacetate
126-14-7
US $40.00 / mg 99.73% 10g TargetMol Chemicals Inc.
Sucrose Octaacetatee pictures 2024-11-04 Sucrose Octaacetatee
126-14-7
US $0.00-0.00 / kg 1kg 99% 20MT Watson Biotechnology Co.,Ltd
Sucrose octaacetate pictures 2024-11-03 Sucrose octaacetate
126-14-7
US $99.00-66.00 / kg 0.001kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
OCTA-O-ACETYL D-(+)-SACCHAROSE OCTA-O-ACETYL D-(+)-SUCROSE Sucrose octa actate SUCROSE OCTAACETATE 97+% OCTAACETYL SUCROSE(SACCHAROSE OCTAACETATE) D-SucroseOctoacetate,>99% D-SucroseOctoacetate SUCROSEOCTAACETATE,NF D-(+)-Sucrose octaacetate, Sucrose octaacetate [(2S,3S,4R,5R)-4-Acetyloxy-2,5-bis(acetyloxymethyl)-2-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxyoxolan-3-yl] acetate 2,3,4,6,1',3',4',6'-Octa-O-acetylsucrose a-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-b-D-fructofuranosyl, tetraacetate Octa-O-acetylsucrose 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl α-D-glucopyranoside 2,3,4,6-tetraacetate 1-O,3-O,4-O,6-O-Tetraacetyl-β-D-fructofuranosyl-α-D-glucopyranoside 2,3,4,6-tetraacetate β-D-Fructofuranosyl α-D-glucopyranoside octaacetate Sucrose octaacetate,98% Sucrose octaacetate Sucrose Octaacetate (500 mg) D-(+)-Saccharose Octaacetate Octa-O-acetyl D-(+)-Saccharose D-(+)-Sucrose Octaacetate Sucrose OCLaacetate (2R,3R,4S,5R,6R)-2-(acetoxyMethyl)-6-(((2S,3S,4R,5R)-3,4-diacetoxy-2,5-bis(acetoxyMethyl)tetrahydrofuran-2-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate Octa-O-acetyl D-(+)-Surcose a-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-b-D-fructofuranosyl, 2,3,4,6-tetraacetate D-(+)-Saccharose octaacetate for synthesis OCTAACETYLSUCROSE SACCHAROSE OCTAACETATE .alpha.-D-Glucopyranoside,1,3,4,6-tetra-O-acetyl-.beta.-D-fructofuranosyl,tetraacetate 1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl-alpha-d-glucopyranosidtetr 1,3,4,6-Tetra-O-acetylhex-2-ulofuranosyl 2,3,4,6-tetra-O-acetylhexopyranoside aacetate alpha-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-beta-D-fructofuranosyl, tetraacetate alpha-d-glucopyranoside,1,3,4,6-tetra-o-acetyl-beta-d-fructofuranosyl,tetra D-(+)-SACCHAROSE OCTAACETATE D-SACCHAROSE OCTAACETATE D-(+)-SUCROSE OCTAACETATE Sucrose octaacetateOCTAACETATE Octa-O-acetyl D-(+)-Sucrose > Octa D α-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-β-D-fructofuranosyl, 2,3,4,6-tetraacetate Sucrose octaacetate USP/EP/BP 204-772-1 High Purity Best Price Sucrose Octaacetate CAS 126-14-7 with Best Price Sucrose octaacetate(USP/NF/CP2020) α-D-Glucopyranoside, 1,3,4,6-tetra-O-acetyl-β-D-fructofuranosyl, 2,3,4,6-tetraacetate SUCROSE OCTACETATE Soa FEMA 3038 bitter taste 2-PHENYLPROPIONALDEHYDE 93-53-8 Octa-O-acetyl D-(+)-Sucrose, ≥ 98.0% Sucrose Octaacetatee Sucrose Octaacetate(USP/NF/ChP) 126-14-7 124-14-7 C28H38O19 C12H14O3OOCCH33 Monosaccharides