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Halobetasol propionate

CAS No.
66852-54-8
Chemical Name:
Halobetasol propionate
Synonyms
CGP-14458;BMY-30056;Ultravate;Miracorten;ulobetasol propionate;Uiobetasol Propionate;Halobatasol Proionate;HALOBETASOL PROPIONATE;HalobetasolPropionate>Halobetasol Propionate (200 mg)
CBNumber:
CB4305095
Molecular Formula:
C25H31ClF2O5
Molecular Weight:
484.96
MDL Number:
MFCD00866013
MOL File:
66852-54-8.mol
MSDS File:
SDS
Last updated:2024-04-01 18:08:31

Halobetasol propionate Properties

Melting point 213-215°C
Boiling point 570.7±50.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 12.55±0.70(Predicted)
color White to Off-White
InChIKey BDSYKGHYMJNPAB-QNGYMBKVNA-N
SMILES O([C@@]1([C@H](C[C@@]2([H])[C@]3([H])C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C)C(=O)CCl)C(=O)CC |&1:1,2,4,6,9,17,19,21,24,r|
CAS DataBase Reference 66852-54-8(CAS DataBase Reference)
FDA UNII 91A0K1TY3Z
Proposition 65 List Halobetasol Propionate

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H372-H341-H361
Precautionary statements  P260-P264-P270-P314-P501-P201-P202-P281-P308+P313-P405-P501-P201-P202-P281-P308+P313-P405-P501
HS Code  2937220000
NFPA 704
0
4 0

Halobetasol propionate price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1302906 Halobetasol propionate United States Pharmacopeia (USP) Reference Standard 66852-54-8 200MG $174.4 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 66852-54-8 5mg $32 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 66852-54-8 10mg $55 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 66852-54-8 25mg $116 2024-03-01 Buy
Cayman Chemical 23781 Halobetasol Propionate ≥95% 66852-54-8 50mg $169 2024-03-01 Buy
Product number Packaging Price Buy
1302906 200MG $174.4 Buy
23781 5mg $32 Buy
23781 10mg $55 Buy
23781 25mg $116 Buy
23781 50mg $169 Buy

Halobetasol propionate Chemical Properties,Uses,Production

Description

Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis.  It inhibits dermatitis induced by ultraviolet light in guinea pigs (ED50 = 1.45 μg/animal) and by oxazolone in mice (ED50 = 0.8 μg/animal). Halobetasol propionate also has anti-inflammatory effects on croton oil-induced ear edema in rats (ED50s = 10 μg/ml and 0.5 μg/ear) and mice (ED50s = 1.2 and <0.32 μg/ear after 6 and 24 hours of treatment, respectively). Topical formulations containing halobetasol propionate have been used for inflammatory and pruritic dermatitis.

Chemical Properties

White Solid

Originator

Ciba-Geigy (Switzerland)

Uses

Halobetasol propionate is a corticosteroid (cortisone-like medicine or steroid). As an anti-inflammatory drug, halobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. It is also used to treat plaque psoriasis.This medicine is available only with doctor's prescription.

Definition

ChEBI: Ulobetasol propionate is a corticosteroid hormone.

brand name

Ultravate (Westwood-Squibb).

Global( 327)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Shizhou Biotechnology Co., Ltd
+86-15850508050 +86-15850508050 sean.lv@synzest.com China 323 58
Wuhan Haorong Biotechnology Co.,ltd
+86-18565342920; +8618565342920 sales@chembj.net China 289 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Hebei shuoxi biotechnology co. LTD
+8613081092107 CHINA 964 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58

View Lastest Price from Halobetasol propionate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Halobetasol propionate pictures 2024-10-25 Halobetasol propionate
66852-54-8
US $0.00-0.00 / KG 1KG 99% 500 Wuhan Haorong Biotechnology Co.,Ltd
Halobetasol propionate pictures 2024-04-02 Halobetasol propionate
66852-54-8
US $0.00 / kg 1kg 99% 20tons Shaanxi TNJONE Pharmaceutical Co., Ltd
Halobetasol propionate pictures 2023-05-20 Halobetasol propionate
66852-54-8
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd

Halobetasol propionate Spectrum

ulobetasol propionate HALOBETASOL PROPIONATE BMY-30056 CGP-14458 Uiobetasol Propionate Ultravate 21-chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate 6 alpha-fluoroclobetasol 17-propionate (6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6-alpha,11-beta,16-beta) Ulobetasol (Halobetasol)Propionate Pregna-1,4-diene-3,20-dione,21-chloro-6,9-difluoro-11-hydroxy-16-Methyl-17-(1-oxopropoxy)-, (6a,11b,16b)- Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6α,11β,16β)- Halobatasol Proionate Halobetasol Propionate (200 mg) Miracorten HalobetasolPropionate> 21-Chloro-6alpha,9alpha-difluoro-11beta,17alpha-dihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17-Propionate Halobetasol propionate ISO 9001:2015 REACH Halobetasol PropionateQ: What is Halobetasol Propionate Q: What is the CAS Number of Halobetasol Propionate Q: What is the storage condition of Halobetasol Propionate Q: What are the applications of Halobetasol Propionate Halobetasol Propionate D5Q: What is Halobetasol Propionate D5 Q: What is the CAS Number of Halobetasol Propionate D5 Halobetasol Propionate (1302906) (6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate 21-chloro-6alpha,9-difChemicalbookluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione17-propionate Halobetasol Propionate|||Ulobetasol propionate|||BMY-30056|||CGP-14458 Halobetasol propionate in Methanol 66852-54-8 C25H31ClF2O5 Inhibitors Steroids