ChemicalBook >> CAS DataBase List >>N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide structure

CAS No.: 1210608-43-7

Chemical Name:: N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide

Synonyms: PIM447;EOS-60671;PIM447 (LGH447);PIM447 (LGH447) Free Base;N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide;2-Pyridinecarboxamide, N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]-3-pyridinyl]-6-(2,6-difluorophenyl)-5-fluoro-

CBNumber:: CB43143070

Molecular Formula:: C24H23F3N4O

Molecular Weight:: 440.46

MDL Number:

MOL File:: 1210608-43-7.mol

Last updated:2024-10-28 16:48:35

Request For Quotation

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide Properties

Boiling point	493.7±45.0 °C(Predicted)
Density	1.290±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO:88.0(Max Conc. mg/mL);199.79(Max Conc. mM) Ethanol:88.0(Max Conc. mg/mL);199.79(Max Conc. mM)
form	Solid
pka	1.35±0.70(Predicted)
color	White to off-white
FDA UNII	9TG5O4V25H

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	P446750	PIM447	1210608-43-7	0.25mg	$185	2021-12-16	Buy
TRC	P446750	PIM447	1210608-43-7	2.5mg	$1025	2021-12-16	Buy
CSNpharm	CSN19123	PIM-447	1210608-43-7	10mg	$480	2021-12-16	Buy

Product number	Packaging	Price	Buy
P446750	0.25mg	$185	Buy
P446750	2.5mg	$1025	Buy
CSN19123	10mg	$480	Buy

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide Chemical Properties,Uses,Production

Uses

PIM kinases promote growth and survival of tumor cells and are expressed in a wide variety of human cancers. These kinases are potential therapeutic targets. PIM447 is a PIM kinase inhibitor.

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide Suppliers

Global( 51)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32956	60
TopScience Biochemical	00852-68527855	info@itopbiochem.com	China Hong Kong	902	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33338	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TopScience Biochemical	58
TargetMol Chemicals Inc.	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
LEAPCHEM CO., LTD.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58

View Lastest Price from N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	PIM447 1210608-43-7	US $1090.00-2950.00 / mg			10g	TargetMol Chemicals Inc.

PIM447
1210608-43-7
US $1090.00-2950.00 / mg
TargetMol Chemicals Inc.

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide PIM447 (LGH447) PIM447 (LGH447) Free Base EOS-60671 2-Pyridinecarboxamide, N-[4-[(1R,3S,5S)-3-amino-5-methylcyclohexyl]-3-pyridinyl]-6-(2,6-difluorophenyl)-5-fluoro- PIM447 1210608-43-7