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S3QEL 2

CAS No.
890888-12-7
Chemical Name:
S3QEL 2
Synonyms
S3QEL 2;1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl-
CBNumber:
CB43146374
Molecular Formula:
C19H25N5
Molecular Weight:
323.44
MDL Number:
MOL File:
890888-12-7.mol
Last updated:2024-07-02 08:55:08

S3QEL 2 Properties

storage temp. Store at -20°C
solubility DMF: 10 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: slightly soluble
form A crystalline solid
color Off-white to yellow

S3QEL 2 price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18556 S3QEL-2 ≥98% 890888-12-7 5mg $37 2024-03-01 Buy
Cayman Chemical 18556 S3QEL-2 ≥98% 890888-12-7 10mg $68 2024-03-01 Buy
Cayman Chemical 18556 S3QEL-2 ≥98% 890888-12-7 25mg $161 2024-03-01 Buy
TRC S030000 S3QEL2 890888-12-7 50mg $250 2021-12-16 Buy
AK Scientific 2878CX 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 890888-12-7 25mg $276 2021-12-16 Buy
Product number Packaging Price Buy
18556 5mg $37 Buy
18556 10mg $68 Buy
18556 25mg $161 Buy
S030000 50mg $250 Buy
2878CX 25mg $276 Buy

S3QEL 2 Chemical Properties,Uses,Production

Description

S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 μM) without altering normal bioenergetics function. It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control level. S3QEL-2 also protects against ROS-induced cell stress in pancreatic β-cells and decreases HIF-1α induction in response to hypoxia.

Uses

S3QEL 2 supresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation.

S3QEL 2 Preparation Products And Raw materials

Raw materials

Preparation Products

S3QEL 2 Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9707 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9294 58
S3QEL 2 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(3,4-dimethylphenyl)-N,N-dipropyl- 890888-12-7