Tezacaftor

Tezacaftor structure

CAS No.: 381212-03-9

Chemical Name:: Tezacaftor

Synonyms: Tezacaftor;Acetamide, 2-[(1S)-1-[(3aS,7aS)-7-[(7E)-2-[(2Z,3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]-3a,4,5,6,7,7a-hexahydro-3a-methyl-1H-inden-3-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)-

CBNumber:: CB43159989

Molecular Formula:: C26H34F5NO4

Molecular Weight:: 519.54

MDL Number:

MOL File:: 381212-03-9.mol

Last updated:2024-01-03 16:56:20

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Tezacaftor Properties

Boiling point	614.0±55.0 °C(Predicted)
Density	1.27±0.1 g/cm3(Predicted)
storage temp.	Refrigerator
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	12.56±0.46(Predicted)
color	White to Light Yellow
FDA UNII	KT5224XSHW

Tezacaftor Chemical Properties,Uses,Production

Uses

Tezacaftor is used as a combination therapy with Ivacaftor for the treatment of patients with cystic fibrosis.

Tezacaftor Preparation Products And Raw materials

Raw materials

Preparation Products

Tezacaftor Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21675	55
Gansu HaoTian Chemical Technology Co., Ltd.	0943-6900332 17789447501	business02@gshtchem.com	China	203	55
Shanghai Biopharmaleader Co., Ltd.	+86 18721201413	sales@biopharmaleader.com	China	1720	58
Zhengzhou Kangshan Biological Co., Ltd.	+86-0371-55023472 +86-13663848272	2584787837@qq.com	China	238	58
Hubei Weideli Chemical Reagent Co.，Ltd.	13339985473	C13339985473@163.com	China	4557	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shaanxi Henghan New Materials Co., Ltd	15619311539	907967238@qq.com	China	2647	58
Pushan Industry (Shaanxi) Co., Ltd	029-81310890 18165209495	2929288192@qq.com	China	9997	58
Hubei Hengluyuan Technology co.ltd	027-88188016 18717196322	1764683941@qq.com	China	4455	58

Supplier	Advantage
Henan Tianfu Chemical Co.,Ltd.	55
Gansu HaoTian Chemical Technology Co., Ltd.	55
Shanghai Biopharmaleader Co., Ltd.	58
Zhengzhou Kangshan Biological Co., Ltd.	58
Hubei Weideli Chemical Reagent Co.，Ltd.	58
TargetMol Chemicals Inc.	58
Shaanxi Henghan New Materials Co., Ltd	58
Pushan Industry (Shaanxi) Co., Ltd	58
Hubei Hengluyuan Technology co.ltd	58

The synthesis method of Tezacaftor
Tezacaftor is a broad-acting CFTR corrector similar to lumacaftor that facilitates the cellular processing and trafficking of ....
Jan 3，2024

Tezacaftor Acetamide, 2-[(1S)-1-[(3aS,7aS)-7-[(7E)-2-[(2Z,3S,5R)-3,5-dihydroxy-2-methylenecyclohexylidene]ethylidene]-3a,4,5,6,7,7a-hexahydro-3a-methyl-1H-inden-3-yl]ethoxy]-N-(2,2,3,3,3-pentafluoropropyl)- 381212-03-9 C26H34F5NO4