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ChemicalBook >> CAS DataBase List >>Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- Structure
Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- structure
CAS No.
134724-87-1
Chemical Name:
Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-
Synonyms
phthalimidooxyacetic acid;2-PHTHALIMIDEHYDROXY-ACETIC ACID;2-(1,3-dioxoisoindol-2-yl)oxyaceticacid;2-((1,3-Dioxoisoindolin-2-yl)oxy)acetic acid;2-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)oxy]acetic acid;Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-;Acetic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-;PROTAC Linkers,inhibit,Inhibitor,2Phthalimidehydroxyacetic acid,2 Phthalimidehydroxy acetic acid
CBNumber:
CB43186851
Molecular Formula:
C10H7NO5
Molecular Weight:
221.16628
MDL Number:
MFCD11850832
MOL File:
134724-87-1.mol
Last updated:2025-04-28 21:36:36
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Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- Properties

Melting point 166-168 °C
Boiling point 434.3±47.0 °C(Predicted)
Density 1.59±0.1 g/cm3(Predicted)
pka 2.70±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H319-H315-H302
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 4081BB PhthalimidooxyaceticAcid 134724-87-1 250mg $432 2021-12-16 Buy
Matrix Scientific 180075 2-((1,3-Dioxoisoindolin-2-yl)oxy)acetic acid 95% 134724-87-1 1g $908 2021-12-16 Buy
Matrix Scientific 180075 2-((1,3-Dioxoisoindolin-2-yl)oxy)acetic acid 95% 134724-87-1 5g $1816 2021-12-16 Buy
A1 Biochem Labs 6569988 2-((1,3-Dioxoisoindolin-2-yl)oxy)aceticacid 95% 134724-87-1 5G $1100 2021-12-16 Buy
Product number Packaging Price Buy
4081BB 250mg $432 Buy
180075 1g $908 Buy
180075 5g $1816 Buy
6569988 5G $1100 Buy

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- Chemical Properties,Uses,Production

Uses

2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- synthesis

54224-25-8
134724-87-1
Synthesis of Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- from tert-butyl 2-(1.3-dioxoisoindolin-2-yloxy)acetate

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- Suppliers

Global( 19)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32239 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Jiangsu aikang biomedical research and development co., LTD 025-66110311 13155353615 qzhang@aikonchem.com China 15526 58
Changzhou Kechem Bio-Scientific Co., LTD. 0519-68985668 13685222090 sales@kechem.cn China 26028 58
TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 sales@tcisct.com China 31121 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29774 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 62072 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24739 58
Beijing FYF Chemicals Co., Ltd 010-57903446 15869909019 168931144@qq.com China 4847 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Jiangsu aikang biomedical research and development co., LTD 58
Changzhou Kechem Bio-Scientific Co., LTD. 58
TCI (Shanghai) Chemical Trading Co., Ltd. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Beijing FYF Chemicals Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

View Lastest Price from Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Phthalimidehydroxy-acetic acid pictures 2025-04-28 2-Phthalimidehydroxy-acetic acid
134724-87-1
 US $42.00 / mg 97.92% 10g TargetMol Chemicals Inc.
Acetic acid, [(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- 2-(1,3-dioxoisoindol-2-yl)oxyaceticacid 2-PHTHALIMIDEHYDROXY-ACETIC ACID 2-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)oxy]acetic acid PROTAC Linkers,inhibit,Inhibitor,2Phthalimidehydroxyacetic acid,2 Phthalimidehydroxy acetic acid Acetic acid, 2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]- phthalimidooxyacetic acid 2-((1,3-Dioxoisoindolin-2-yl)oxy)acetic acid 134724-87-1 3134724-87-1