ChemicalBook >> CAS DataBase List >>LCRF-0004
LCRF-0004
- CAS No.
- 1229611-73-7
- Chemical Name:
- LCRF-0004
- Synonyms
- LCRF-0004;1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-1-phenyl-5-(trifluoromethyl)-
- CBNumber:
- CB43303238
- Molecular Formula:
- C28H18F4N6O2S
- Molecular Weight:
- 578.54
- MDL Number:
- MOL File:
- 1229611-73-7.mol
Last updated:2024-10-23 13:36:13
LCRF-0004 Chemical Properties,Uses,Production
Description
LCRF-0004 is a potent and selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is overexpressed in the majority of pancreatic cancers. Preclinical studies show that inhibition of RON function decreases pancreatic cancer cell migration, invasion, and survival and can sensitize pancreatic cancer cells to chemotherapy. RON receptor tyrosine kinase is a potential as a therapeutic target.
LCRF-0004 Preparation Products And Raw materials
Raw materials
Preparation Products
LCRF-0004 Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19711 | 58 |
Supplier | Advantage |
---|---|
TargetMol Chemicals Inc. | 58 |
TargetMol Chemicals Inc. | 58 |
LCRF-0004
1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-1-phenyl-5-(trifluoromethyl)-
1229611-73-7