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LCRF-0004

CAS No.
1229611-73-7
Chemical Name:
LCRF-0004
Synonyms
LCRF-0004;1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-1-phenyl-5-(trifluoromethyl)-
CBNumber:
CB43303238
Molecular Formula:
C28H18F4N6O2S
Molecular Weight:
578.54
MDL Number:
MOL File:
1229611-73-7.mol
Last updated:2024-10-23 13:36:13

LCRF-0004 Properties

Boiling point 680.6±55.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
pka 10.07±0.70(Predicted)

LCRF-0004 Chemical Properties,Uses,Production

Description

LCRF-0004 is a potent and selective RON receptor tyrosine kinase inhibitor. The RON receptor tyrosine kinase has been identified as an important mediator of KRAS oncogene addiction and is overexpressed in the majority of pancreatic cancers. Preclinical studies show that inhibition of RON function decreases pancreatic cancer cell migration, invasion, and survival and can sensitize pancreatic cancer cells to chemotherapy. RON receptor tyrosine kinase is a potential as a therapeutic target.

LCRF-0004 Preparation Products And Raw materials

Raw materials

Preparation Products

LCRF-0004 Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19711 58

View Lastest Price from LCRF-0004 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LCRF-0004 pictures 2024-10-24 LCRF-0004
1229611-73-7
US $1520.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • LCRF-0004 pictures
  • LCRF-0004
    1229611-73-7
  • US $1520.00-2500.00 / mg
  • TargetMol Chemicals Inc.
LCRF-0004 1H-Pyrazole-4-carboxamide, N-[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-1-phenyl-5-(trifluoromethyl)- 1229611-73-7