ChemicalBook >> CAS DataBase List >>GC376
GC376
- CAS No.
- 1416992-39-6
- Chemical Name:
- GC376
- Synonyms
- 376;GC376 sodium;GC376;GPC376;GC376 Sodium Bulk;GC376 (sodium salt);GC-376 sodium,GC376 sodium;3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid;sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4- methylpentanamido)- 1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane- 1-;Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
- CBNumber:
- CB43333611
- Molecular Formula:
- C21H32N3NaO8S
- Molecular Weight:
- 509.55
- MDL Number:
- MFCD31382192
- MOL File:
- 1416992-39-6.mol
Last updated:2023-09-08 17:00:39
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
---|---|
solubility | DMF: 10 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
form | A crystalline solid |
FDA UNII | H1NMJ5XDG5 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P280-P301+P312-P304+P340 |
HS Code | 2933299090 |
GC376 price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Biosynth Carbosynth | BG167367 | GC 376 sodium | 1416992-39-6 | 25mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG167367 | GC 376 sodium | 1416992-39-6 | 50mg | $120 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG167367 | GC 376 sodium | 1416992-39-6 | 100mg | $180 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG167367 | GC 376 sodium | 1416992-39-6 | 250mg | $350 | 2021-12-16 | Buy |
Biosynth Carbosynth | BG167367 | GC 376 sodium | 1416992-39-6 | 500mg | $650 | 2021-12-16 | Buy |
GC376 Chemical Properties,Uses,Production
Description
GC376 is an inhibitor of the main protease Mpro (3CLpro) in coronaviruses as well as picornaviruses. This broad-spectrum antiviral compound has been used as investigational veterinary drug for treatment of feline infectious peritonitis virus (FIPV) infections. Recent studies also showed that GC376 inhibits the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.03 μM and EC50 of 3.37 μM.
Uses
GC 376 sodium is a potential small molecule inhibitor which may be able to reduce the viral load of SARS-CoV-2 3CLpro.
Synthesis of GC376 from benzyl ((2S)-4-methyl-1-oxo-1-(((2S)-1-oxo-3-(2-oxo-1l2-pyrrolidin-3-yl)propan-2-yl)-l2-azanyl)pentan-2-yl)carbamate
GC376 Preparation Products And Raw materials
Global( 99)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shandong Natural Micron Pharm Tech Co.,LTD | +86-18653895227 | info@nmpharmtech.com | China | 94 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29821 | 58 |
Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
Wuhan Nutra Biotechnology Co.,Ltd | +8617786394783 | nutrabiotech@outlook.com | China | 300 | 58 |
Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 13234 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
View Lastest Price from GC376 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-09-08 | GC376
1416992-39-6
|
US $30.00 / kg | 1kg | 99% | 1000t/year | Anhui Ruihan Technology Co., Ltd | ||
2021-10-08 | GC376;GC-376 sodium
1416992-39-6
|
US $1.00-0.00 / g | 1ASSAYS | 98%+ | 10kgs | Wuhan Nutra Biotechnology Co.,Ltd | ||
2019-12-31 | GC376 sodium
1416992-39-6
|
US $6.60 / KG | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
- GC376
1416992-39-6
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
- GC376;GC-376 sodium
1416992-39-6
- US $1.00-0.00 / g
- 98%+
- Wuhan Nutra Biotechnology Co.,Ltd
- GC376 sodium
1416992-39-6
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co
GC376
GPC376
3 alpha, 7 alpha-dyhydroxy-6-ethidene- cholanic acid
Sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-methylpentanamido)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate
(βS)-α-Hydroxy-β-[[(2S)-4-methyl-1-oxo-2-[[(phenylmethoxy)carbonyl]amino]pentyl]amino]-2-oxo-3-pyrrolidinepropanesulfonic acid sodium salt
376
GC376 sodium
GC376 (sodium salt)
GC-376 sodium,GC376 sodium
sodium (2S)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-
methylpentanamido)- 1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane- 1-
GC376 Sodium Bulk
1416992-39-6
1416882-39-6