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ChemicalBook >> CAS DataBase List >>5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Structure
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester structure
CAS No.
391610-37-0
Chemical Name:
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester
Synonyms
MCHr1 antagonist 1;MCHR1 antagonist 1,MCHR-1 antagonist 1;methyl 4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-((3-(4-(pyridin-2-yl)piperidin-1-yl)propyl)carbamoyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate;5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester
CBNumber:
CB43339592
Molecular Formula:
C28H33F2N5O5
Molecular Weight:
557.5889264
MDL Number:
MFCD31382100
MOL File:
391610-37-0.mol
Last updated:2023-05-21 10:59:17
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5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Properties

storage temp. Store at -20°C
solubility Soluble in DMSO

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
CSNpharm CSN23711 MCHr1Antagonist1 391610-37-0 1mg $1229 2021-12-16 Buy
CSNpharm CSN23711 MCHr1Antagonist1 391610-37-0 5mg $2458 2021-12-16 Buy
CSNpharm CSN23711 MCHr1Antagonist1 391610-37-0 10mg $4176 2021-12-16 Buy
CSNpharm CSN23711 MCHr1Antagonist1 391610-37-0 25mg $7373 2021-12-16 Buy
Product number Packaging Price Buy
CSN23711 1mg $1229 Buy
CSN23711 5mg $2458 Buy
CSN23711 10mg $4176 Buy
CSN23711 25mg $7373 Buy

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Chemical Properties,Uses,Production

Description

MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.

MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].

References

[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester Suppliers

Global( 7)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19994 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
BOC Sciences -- info@bocsci.com USA 0 65
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; psaitong@jm-bio.com China 29778 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Labnetwork lnc. 		58
MedChemexpress LLC 58
Fan De(Beijing) Biotechnology Co., Ltd. 58
BOC Sciences 65
Beijing Jin Ming Biotechnology Co., Ltd. 58
5-Pyrimidinecarboxylic acid, 6-(3,4-difluorophenyl)-1,2,3,6-tetrahydro-4-(methoxymethyl)-2-oxo-1-[[[3-[4-(2-pyridinyl)-1-piperidinyl]propyl]amino]carbonyl]-, methyl ester methyl 4-(3,4-difluorophenyl)-6-(methoxymethyl)-2-oxo-3-((3-(4-(pyridin-2-yl)piperidin-1-yl)propyl)carbamoyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate MCHr1 antagonist 1 MCHR1 antagonist 1,MCHR-1 antagonist 1 391610-37-0