ChemicalBook >> CAS DataBase List >>{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester structure

CAS No.: 1807521-06-7

Chemical Name:: {2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester

Synonyms: Ph-Bis(C1-N-(C2-NH-Boc)2);{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester;tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate;10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester

CBNumber:: CB43363807

Molecular Formula:: C36H64N6O8

Molecular Weight:: 708.93

MDL Number:: MFCD28142457

MOL File:: 1807521-06-7.mol

Last updated:2023-07-12 17:26:49

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{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Properties

Boiling point	775.5±60.0 °C(Predicted)
Density	1.093±0.06 g/cm3(Predicted)
pka	11.79±0.46(Predicted)

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
BroadPharm	BP-22351	{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester 96%	1807521-06-7	100mg	$350	2021-12-16	Buy
Apolloscientific	OR323158	{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester	1807521-06-7	100mg	$731	2021-12-16	Buy
SynQuest Laboratories	4656-1-3H	tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate	1807521-06-7	100mg	$807	2021-12-16	Buy
BroadPharm	BP-22351	{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester 96%	1807521-06-7	500mg	$980	2021-12-16	Buy
BroadPharm	BP-22351	{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamicacidtert-butylester 96%	1807521-06-7	1g	$1470	2021-12-16	Buy

Product number	Packaging	Price	Buy
BP-22351	100mg	$350	Buy
OR323158	100mg	$731	Buy
4656-1-3H	100mg	$807	Buy
BP-22351	500mg	$980	Buy
BP-22351	1g	$1470	Buy

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Chemical Properties,Uses,Production

Biological Activity

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Jinan elephant international trading co., LTD		13006575422@163.com	China	6357	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85563444 18351873721	purchase@synzest.com	China	10441	58
Zhengzhou Akem Chemical Co., Ltd	13303867194	3001317055@qq.com	China	9624	58
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840	psaitong@jm-bio.com	China	29778	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	0431-80514535 19917294565	et@chemextension.com	China	5061	58
Jilin Chinese Academy of Sciences-yanshen Technology	18143011203	ET-market@chemextension.com	China	41850	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Aladdin Scientific	58
Jinan elephant international trading co., LTD	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Zhengzhou Akem Chemical Co., Ltd	58
Beijing Jin Ming Biotechnology Co., Ltd.	58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd	58
Jilin Chinese Academy of Sciences-yanshen Technology	58

{2-[(4-{[Bis-(2-tert-butoxycarbonylamino-ethyl)-amino]-methyl}-benzyl)-(2-tert-butoxycarbonylamino-ethyl)-amino]-ethyl}-carbamic acid tert-butyl ester tert-Butyl N-(2-{[(4-{[bis(2-{[(tert-butoxy)carbonyl]amino}ethyl)amino]methyl}phenyl)methyl](2-{[(tert-butoxy)carbonyl]amino}ethyl)amino}ethyl)carbamate Ph-Bis(C1-N-(C2-NH-Boc)2) 10-Oxa-2,5,8-triazadodecanoic acid, 5-[[4-[[bis[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]amino]methyl]phenyl]methyl]-11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester 1807521-06-7