Propargyl-PEG1-SS-PEG1-PFP ester
- CAS No.
- 1817735-30-0
- Chemical Name:
- Propargyl-PEG1-SS-PEG1-PFP ester
- Synonyms
- Propargyl-PEG1-SS-PEG1-PFP ester;perfluorophenyl 3-(2-((2-(prop-2-yn-1-yloxy)ethyl)disulfaneyl)ethoxy)propanoate;Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
- CBNumber:
- CB43363988
- Molecular Formula:
- C16H15F5O4S2
- Molecular Weight:
- 430.41
- MDL Number:
- MFCD29042354
- MOL File:
- 1817735-30-0.mol
Propargyl-PEG1-SS-PEG1-PFP ester Chemical Properties,Uses,Production
Description
Propargyl-PEG1-SS-PEG1-PFP ester is a Click Chemistry crosslinker. PFP ester is reactive with amine-bearing molecule. The propargyl groups can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages.
Uses
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Disulfide Cleavable Linker; Cleavable Linker
References
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Propargyl-PEG1-SS-PEG1-PFP ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG1-SS-PEG1-PFP ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3148 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Jinan elephant international trading co., LTD | 13006575422@163.com | China | 6355 | 58 | |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12306 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4838 | 58 |
| Hangzhou Taorui Biotechnology Co., Ltd | 4000-360-990 15268198094 | sales@torreybio.com | China | 3271 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9964 | 58 |
View Lastest Price from Propargyl-PEG1-SS-PEG1-PFP ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-21 | Propargyl-PEG1-SS-PEG1-PFP ester
1817735-30-0
|
US $0.00 / mg | 50mg | >95.00% | 50mg | Xian confluore Biological Technology Co., Ltd. |
-
- Propargyl-PEG1-SS-PEG1-PFP ester
1817735-30-0
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
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