beta-Sitosterol
- CAS No.
- 83-46-5
- Chemical Name:
- beta-Sitosterol
- Synonyms
- β-Sitosterol;SITOSTEROL;PHYTOSTEROL;B-SITOSTEROL;22,23-DIHYDROSTIGMASTEROL;Sterol;Stigmast-5-en-3beta-ol;sobatum;Quebrachol;nimbosterol
- CBNumber:
- CB4345688
- Molecular Formula:
- C29H50O
- Molecular Weight:
- 414.72
- MDL Number:
- MFCD00003631
- MOL File:
- 83-46-5.mol
- MSDS File:
- SDS
| Melting point | 136-140 °C(lit.) |
|---|---|
| alpha | -28 º (c=2, CHCl3) |
| Boiling point | 473.52°C (rough estimate) |
| Density | 0.9540 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | 2-8°C |
| solubility | chloroform: 20 mg/mL, clear, colorless |
| pka | 15.03±0.70(Predicted) |
| form | White solid |
| color | White to Off-White |
| optical activity | -3725 (c 2, CHCl3) |
| Water Solubility | INSOLUBLE |
| Merck | 14,8556 |
| BRN | 1916165 |
| InChIKey | KZJWDPNRJALLNS-VJSFXXLFSA-N |
| LogP | 10.482 (est) |
| CAS DataBase Reference | 83-46-5(CAS DataBase Reference) |
| NCI Dictionary of Cancer Terms | beta-sitosterol |
| FDA UNII | S347WMO6M4 |
| NIST Chemistry Reference | «beta»-Sitosterol(83-46-5) |
| EPA Substance Registry System | .beta.-Sitosterol (83-46-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H319-H331-H336-H351-H361d-H372-H412 |
| Precautionary statements | P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313 |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-38-40-48/20/22-36/37/38-67-36/38-20-63 |
| Safety Statements | 22-24/25-36-26-36/37 |
| RIDADR | UN 1888 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | WJ2600000 |
| F | 10 |
| HS Code | 29061990 |
beta-Sitosterol price More Price(65)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2693 | β-Sitosterol Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200?mg | 83-46-5 | 200MG | $292 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL89283 | β-Sitosterol phyproof? Reference Substance | 83-46-5 | 25MG | $377 | 2024-03-01 | Buy |
| Sigma-Aldrich | 567152 | β-Sitosterol - CAS 83-46-5 - Calbiochem Common plant steroid that possesses anticholesteremic properties. | 83-46-5 | 5G | $54.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 567152 | β-Sitosterol - CAS 83-46-5 - Calbiochem Common plant steroid that possesses anticholesteremic properties. | 83-46-5 | 25G | $239 | 2024-03-01 | Buy |
| Sigma-Aldrich | 47133 | β-Sitosterol certified reference material, 100?μg/mL in chloroform | 83-46-5 | 1mL | $45.5 | 2024-03-01 | Buy |
beta-Sitosterol Chemical Properties,Uses,Production
Description
24α-ethyl Cholesterol is a naturally occurring plant sterol with antioxidant, anticancer, anti-
Chemical Properties
White powder
Uses
A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma.This compound is a contaminant of emerging concern (CECs)
Uses
antiinflammatory, immunomodulator
Definition
ChEBI: A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3.
Definition
sterol: Any of a group of steroidbasedalcohols having a hydrocarbonside-chain of 8–10 carbon atoms.Sterols exist either as free sterols oras esters of fatty acids. Animal sterols(zoosterols) include cholesterol andlanosterol. The major plant sterol(phytosterol) is beta-sitosterol, whilefungal sterols (mycosterols) includeergosterol.
Definition
A steroid with long aliphatic side chains (8–10 carbons) and at least one hydroxyl group. They are lipidsoluble and often occur in membranes. Examples are cholesterol and ergosterol.
General Description
Sitosterol, also called as β-sitosterol, is synthesized through the mevalonate and deoxy xylulose pathways. Synthetically, it is synthesized from stigmasterol by Δ22–23 alkene group hydrogenation. Structurally sitosterol differ from cholesterol with ethyl (sitosterol) group in C24 position of side chain(65). Sitosterol is a lipid component of membranes. It corresponds to a molecular mass of 414.71 g/mol).
Biochem/physiol Actions
Sitosterol promotes the antioxidant levels and is used as an effective anti-inflammatory, antiapoptotic and anticancer agent in medicinal preparations. It acts as a neutralizing agent for the venom from viper and cobra. Sitosterol acts on protein kinase C (PKC) and in the sphingomyelin cycle to mediate tumor progression inhibition.
Purification Methods
Crystallise -sitosterol from EtOH, MeOH, Me2CO, Me2CO/EtOH or Me2CO/MeOH. It has also been purified by zone melting. The acetate crystallises from MeOH or EtOH as plates with m 127128o and [] D 20 -41o (c 2, CHCl3). The benzoate crystallises from EtOH as needles with m 146-147o and [] D 20 –13.8o (c 2, CHCl3). [Fujimoto & Jacobson J Org Chem 29 3377, 3381 1964, Shoppee J Chem Soc 10431948, Heilbron et al. J Chem Soc 344, 347 1941, Beilstein 6 III 2696.]
beta-Sitosterol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 997 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5893 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 | sales06@hbduling.cn | China | 8053 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | sales02@sdzhonghuimaterial.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | clara@hbshengyang.com | China | 874 | 58 |
| HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +86-15350851019 +86-15383190639 | admin@86-ss.com | China | 1000 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
Related articles
- Beta-Sitosterol: Sources, Extraction Methods and Pharmacokinetics
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- Jun 12，2024
View Lastest Price from beta-Sitosterol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-24 | beta-Sitosterol
83-46-5
|
US $100.00-75.00 / kg | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2024-11-22 | beta-Sitosterol
83-46-5
|
US $20.00 / kg | 1kg | 99% | 5000kg/Week | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2024-11-22 | beta-Sitosterol
83-46-5
|
US $0.00 / Kg/Drum | 1KG | 80% β-Sitosterol | 100KGS | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- beta-Sitosterol
83-46-5
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- beta-Sitosterol
83-46-5
- US $20.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- beta-Sitosterol
83-46-5
- US $0.00 / Kg/Drum
- 80% β-Sitosterol
- WUHAN FORTUNA CHEMICAL CO., LTD
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