Mezlocillin sodium
- CAS No.
- 59798-30-0
- Chemical Name:
- Mezlocillin sodium
- Synonyms
- Chebi:52067;MEZLOCILLIN SODIUM;Mezlocillin Baypen;Meloxicillin sodium;Sodium salt monohydrate;Mezlocillin (sodium salt);Mezlocillin Sodium (350 mg);Mezlocillin sodium USP/EP/BP;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}penicillanate;Sodium 6beta-{(2R)-2-[3-(methanesulfonyl)-2-oxoimidazolidine-1-carboxamido]-2-phenylacetamido}-2,2-dimethylpenam-3alpha-carboxylate
- CBNumber:
- CB4353793
- Molecular Formula:
- C22H27N6NaO9S2
- Molecular Weight:
- 606.6
- MDL Number:
- MFCD07793332
- MOL File:
- 59798-30-0.mol
| Melting point | 197-201°C (dec.) |
|---|---|
| storage temp. | Refrigerator |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | Soluble in water or DMSO |
| CAS DataBase Reference | 59798-30-0(CAS DataBase Reference) |
| FDA UNII | RX227TP94U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H334 |
| Precautionary statements | P261-P285-P304+P341-P342+P311-P501 |
Mezlocillin sodium price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J66306 | Mezlocillin sodium salt | 59798-30-0 | 100mg | $215 | 2024-03-01 | Buy |
| Alfa Aesar | J66306 | Mezlocillin sodium salt | 59798-30-0 | 500mg | $515 | 2021-12-16 | Buy |
| Cayman Chemical | 30691 | Mezlocillin (sodium salt) | 59798-30-0 | 500mg | $290 | 2024-03-01 | Buy |
| Cayman Chemical | 30691 | Mezlocillin (sodium salt) | 59798-30-0 | 1g | $547 | 2024-03-01 | Buy |
| Cayman Chemical | 30691 | Mezlocillin (sodium salt) | 59798-30-0 | 250mg | $153 | 2024-03-01 | Buy |
Mezlocillin sodium Chemical Properties,Uses,Production
Description
Mezlocillin is a β-lactam antibiotic and derivative of ampicillin . It is active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 μg/ml, respectively). Mezlocillin (32 μg/ml) is also active against 10 strains of S. faecalis. In vivo, mezlocillin (240 mg/kg) increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis. It completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection when administered at a dose of 300 mg/kg. Formulations containing mezlocillin have been used in the treatment of various bacterial infections.
Chemical Properties
Mezlocillin sodium is white to slightly yellow cryst. powder
Uses
Antibacterial.
Uses
Mezlocillin Sodium (cas# 59798-30-0) is a derivative of penicillin and an antimicrobial.
Definition
ChEBI: Mezlocillin sodium is an organic sodium salt. It contains a mezlocillin(1-).
brand name
Mezlin (Bayer).
Clinical Use
Mezlocillin (Mezlin) is an acylureidopenicillin with an antibacterialspectrum similar to that of carbenicillin andticarcillin; however, there are some major differences. It ismuch more active against most Klebsiella spp., P. aeruginosa,anaerobic bacteria (e.g., Streptococcus faecalis andB. fragilis), and H. influenzae. It is recommended for thetreatment of serious infections caused by these organisms.
Mezlocillin is not generally effective against β-lactamase–producing bacteria, nor is it active orally. It isavailable as a white, crystalline, water-soluble sodium saltfor injection. Solutions should be prepared freshly and, ifnot used within 24 hours, refrigerated. Mezlocillin and otheracylureidopenicillins, unlike carbenicillin, exhibit nonlinearpharmacokinetics. Peak plasma levels, half-life, and areaunder the time curve increase with increased dosage.Mezlocillin has less effect on bleeding time than carbenicillin,and it is less likely to cause hypokalemia.
Mezlocillin sodium Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8812 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12840 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29884 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8618959220845 | sales@amoychem.com | China | 6383 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17365 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34553 | 58 |
View Lastest Price from Mezlocillin sodium manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-21 | Mezlocillin Sodium
59798-30-0
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Weibang Biotechnology Co., Ltd | |
 |
2024-04-29 | Mezlocillin Sodium
59798-30-0
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd | |
 |
2024-04-22 | Mezlocillin Sodium
59798-30-0
|
US $10.00 / kg | 1kg | 99.912% | 10ton | Ouhuang Engineering Materials (Hubei) Co., Ltd |
-
- Mezlocillin Sodium
59798-30-0
- US $10.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd
-
- Mezlocillin Sodium
59798-30-0
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Mezlocillin Sodium
59798-30-0
- US $10.00 / kg
- 99.912%
- Ouhuang Engineering Materials (Hubei) Co., Ltd