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2,4-Dihydroxyacetophenone

2,4-Dihydroxyacetophenone Structure
2,4-Dihydroxyacetophenone structure
CAS No.
89-84-9
Chemical Name:
2,4-Dihydroxyacetophenone
Synonyms
1-(2,4-dihydroxyphenyl)ethanone;Ethanone, 1-(2,4-dihydroxyphenyl)-;RESACETOPHENONE;2,4-DHAP;HyMechroMone;NSC 37559;NSC 10883;AKOS 90593;Resoacetophenone;4-Acetoresorcinol
CBNumber:
CB4391766
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
MDL Number:
MFCD00002279
MOL File:
89-84-9.mol
MSDS File:
SDS
Last updated:2024-12-18 14:08:52
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2,4-Dihydroxyacetophenone Properties

Melting point 143-144.5 °C(lit.)
Boiling point 234.6°C (rough estimate)
Density 1.18 g/mL at 25 °C(lit.)
refractive index 1.4945 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder or Crystals
pka 7.96±0.18(Predicted)
color Off-white to pink to brown
PH 5 (1g/l, H2O, 20℃)
Sensitive Moisture Sensitive
Merck 14,8140
BRN 1282505
InChIKey SULYEHHGGXARJS-UHFFFAOYSA-N
LogP 1.480 (est)
CAS DataBase Reference 89-84-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII UC3V356VZC
NIST Chemistry Reference Ethanone, 1-(2,4-dihydroxyphenyl)-(89-84-9)
EPA Substance Registry System Ethanone, 1-(2,4-dihydroxyphenyl)- (89-84-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
WGK Germany  2
RTECS  AM7525000
Hazard Note  Irritant
TSCA  Yes
HS Code  29145000
NFPA 704
0
1 0

2,4-Dihydroxyacetophenone price More Price(40)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D107409 2′,4′-Dihydroxyacetophenone 99% 89-84-9 100g $93.9 2024-03-01 Buy
Sigma-Aldrich D107409 2′,4′-Dihydroxyacetophenone 99% 89-84-9 500g $110.4 2024-03-01 Buy
TCI Chemical D0561 2',4'-Dihydroxyacetophenone >98.0%(GC)(T) 89-84-9 25g $47 2024-03-01 Buy
TCI Chemical D0561 2',4'-Dihydroxyacetophenone >98.0%(GC)(T) 89-84-9 100g $120 2024-03-01 Buy
Alfa Aesar A12066 2',4'-Dihydroxyacetophenone, 98% 89-84-9 50g $37.65 2024-03-01 Buy
Product number Packaging Price Buy
D107409 100g $93.9 Buy
D107409 500g $110.4 Buy
D0561 25g $47 Buy
D0561 100g $120 Buy
A12066 50g $37.65 Buy

2,4-Dihydroxyacetophenone Chemical Properties,Uses,Production

Chemical Properties

2,4-Dihydroxyacetophenone appears as a yellow-brown to reddish-brown fine crystalline powder. It slowly decomposes in water and can dissolve in hot alcohol, pyridine, and glacial acetic acid. In contrast, it is nearly insoluble in ether, benzene, and chloroform. A reaction with iron chloride causes it to adopt a red hue.

Uses

2,4-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis. It is also used as intermediate for pharmaceuticals. Reagent for iron as a 10% alcoholic solution. A red color is obtained with ferric ions in slightly acid solution: Cooper, Ind. Eng. Chem. Anal. Ed. 9, 334 (1937).

Preparation

Preparation by reaction of acetic acid on resorcinol,
with zinc chloride (Nencki reaction) (94%)
with boron trifluoride
with Amberlite IR-120 (a cation exchange resin, sulfonic acid type) (87%)
with polyphosphoric acid (63%)
with 70% perchloric acid (33%).

Definition

ChEBI: 2',4'-dihydroxyacetophenone is a dihydroxyacetophenone that is acetophenone carrying hydroxy substituents at positions 2' and 4'. It has a role as a plant metabolite. It is a member of resorcinols and a dihydroxyacetophenone.

Synthesis Reference(s)

Journal of the American Chemical Society, 70, p. 428, 1948 DOI: 10.1021/ja01181a521

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. A severe eye irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Synthesis

2,4-Dihydroxyacetophenone is obtained by the acetylation of resorcinol and acetic acid. In addition, it can also be obtained by reacting resorcinol with chloroacetyl or acetic anhydride in the presence of zinc chloride.

target

Phospholipase (e.g. PLA)

2,4-Dihydroxyacetophenone Preparation Products And Raw materials

Raw materials

Zinc chloride Benzene

Preparation Products

7-Hydroxycoumarin 1-[4-(Benzoyloxy)-2-hydroxyphenyl]-3-phenyl-1,3-propanedione 1-(2,4-Bis(benzoyloxy)phenyl)ethanone 7-HYDROXYFLAVONE 2',4'-DIHYDROXYCHALCONE
3,7-DIHYDROXYFLAVONE 4-HYDROXY-7-METHOXYCOUMARIN 7-HYDROXYFLAVANONE ROBINETIN 4'-Benzyloxy-2'-hydroxyacetophenone
4-Ethylresorcinol 4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol 2,4-Dimethoxyacetophenone

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2,4-Dihydroxyacetophenone Suppliers

Global( 657)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8807 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5857 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630 bess@weibangbio.com China 18151 58
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 427 58
Anhui Yiao New Material Technology Co., Ltd 		+86-18033737140 +86-17354101231 sales1@hbganmiao.com China 227 58
Xiamen Work-For-World Medicine Co.,Ltd. 		+8615921822462 co@wfwmed.com China 416 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 +86-16264648883 niki@zlchemi.com China 2886 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
Supplier Advantage
Hebei Weibang Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Weibang Biotechnology Co., Ltd 		58
Firsky International Trade (Wuhan) Co., Ltd 		58
Anhui Yiao New Material Technology Co., Ltd 		58
Xiamen Work-For-World Medicine Co.,Ltd. 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55

View Lastest Price from 2,4-Dihydroxyacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-Dihydroxyacetophenone pictures 2024-12-25 2,4-Dihydroxyacetophenone
89-84-9
 US $55.00 / kg 1kg 99% 20 tons Hebei Zhuanglai Chemical Trading Co Ltd
2,4-Dihydroxyacetophenone pictures 2024-12-13 2,4-Dihydroxyacetophenone
89-84-9
 US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2,4-Dihydroxyacetophenone pictures 2024-10-31 2,4-Dihydroxyacetophenone
89-84-9
 US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Weibang Biotechnology Co., Ltd

2,4-Dihydroxyacetophenone Spectrum

2,4-Dihydroxyacetophenone(89-84-9)MS2,4-Dihydroxyacetophenone(89-84-9)1HNMR2,4-Dihydroxyacetophenone(89-84-9)IR12,4-Dihydroxyacetophenone(89-84-9)Raman

89-84-9(2,4-Dihydroxyacetophenone)Related Search:

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Resoacetophenone Resorcinol, 4-acetyl- 2,4-Dihydroxyacetoph NSC 10883 NSC 37559 4-Acetylresorcinol Resacetophenone IMp. A (EP): 1,3-Dihydroxybenzene (Resorcinol) IMp. B (EP): 7-Hydroxy-2-Methyl-4H-1-benzopyran-4-one 2,4- twohydroxyAcetophenone 2',4'-Dihydroxyacetophenone, 97+% 2,4-Dihydroxy acetophenone (2-acetyl resorcinol) 2"4"-DIHYDROXYACETOPHENONERESACETOPHENONE 2',4'-Dihydroxyacetophenone 4-Acetylresorcinol 2,4-Dihydroxyacetophenone 2,4-Dihydroxyacetophenone,99% 2,4-DIHYDROXYACETOPHENONE extrapure 1-Acetyl-2,4-dihydroxybenzene, 4-Acetylresorcinol, Resacetophenone 2,4-Dihydroxylacetophenone 2-Acetyl-1,5-benzenediol 4-Acetoresorcinol 2',4'-Dihydroxyacetophenone,98% 2',4'-Dihydroxyacetophenone≥ 99% (HPLC) 2,4-DIHYDROXY ACETPHENONE 2',4'-DIHYDROXYACETOPHENONE 2,4-DIHYDROXYACETOPHENONE 1-ACETYL-2,4-DIHYDROXYBENZENE AKOS BBS-00004294 AKOS 90593 1-(2,4-dihydroxyphenyl)-ethanon 1-(2,4-Dihydroxyphenyl)-ethanone 1-Acetylbenzene-2,4-diol 2’,4’-dihydroxy-acetophenon 4-Acetyl-1,3-benzenediol 4-acetyl-resorcino Acetophenone, 2',4'-dihydroxy- beta-Resacetophenone b-Resacetophenone 4-ACETYLRESORCINOL 2,4-Dihydroxyacetophenone C8H8O3 2',4'-Dihydroxyacetophenone > High quality 2,4-Dihydroxyacetophenone Resorcinol Impurity 3 2,4-Dihydroxy-Acetophenone (Resacetophenone -99%) 89-84-9 2,4-Dihydroxyacetophenone 2,4-DIHYDROXY ACETOPHENONE For Synthesis HyMechroMone Ethanone, 1-(2,4-dihydroxyphenyl)- 1-(2,4-dihydroxyphenyl)ethanone RESACETOPHENONE 2,4-DHAP +C1Resacetophenone 2',4'-Dihydroxyacetophenone 2',4'-Dihydroxyacetophenone(Resacetophenone) 2,4-Dihydroxy Acetophenone 98% For Synthesis 89-84-9 98-84-9 CH3COC6H3OH2 KETONE Building Blocks