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ChemicalBook >> CAS DataBase List >>(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide Structure
(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide structure
CAS No.
1282618-08-9
Chemical Name:
(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide
Synonyms
(R)-(+)-Docosahexaenyl-1’(R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide;(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide;4,7,10,13,16,19-Docosahexaenamide, N-[(1R)-2-hydroxy-1-methylethyl]-, (4Z,7Z,10Z,13Z,16Z,19Z)-
CBNumber:
CB43927438
Molecular Formula:
C25H39NO2
Molecular Weight:
385.58266
MDL Number:
MFCD28138457
MOL File:
1282618-08-9.mol
Last updated:2023-07-14 08:28:42
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(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide Properties

Boiling point 551.3±50.0 °C(Predicted)
Density 0.948±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 2 mg/ml; DMSO: 14 mg/ml; Ethanol: 14 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
pka 14.50±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 9001229 (R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide ≥98% 1282618-08-9 1mg $81 2024-03-01 Buy
Cayman Chemical 9001229 (R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide ≥98% 1282618-08-9 5mg $356 2024-03-01 Buy
Cayman Chemical 9001229 (R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide ≥98% 1282618-08-9 10mg $632 2024-03-01 Buy
TRC D494555 (R)-(+)-Docosahexaenyl-1''-Hydroxy-2''-Propylamide 1282618-08-9 2.5mg $130 2021-12-16 Buy
TRC D494555 (R)-(+)-Docosahexaenyl-1''-Hydroxy-2''-Propylamide 1282618-08-9 25mg $1050 2021-12-16 Buy
Product number Packaging Price Buy
9001229 1mg $81 Buy
9001229 5mg $356 Buy
9001229 10mg $632 Buy
D494555 2.5mg $130 Buy
D494555 25mg $1050 Buy

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide Chemical Properties,Uses,Production

Description

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Docosahexaenoyl ethanolamide (DHEA) has potential signaling roles in cancer, inflammation, and neurological development and functioning. At least some of DHEA’s effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists and voltage-gated K+ channel blockers. (R)-(+)-Docosahexaenyl-1’-hydroxy-2’-propylamide is a homolog of DHEA, characterized by the addition of an (R)-α-methyl group at the methylene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce R-1 methanandamide imparts higher affinity for the CB receptor as well as improved metabolic stability. The physiological actions of this compound have not been evaluated.

Uses

(R)-(+)-Docosahexaenyl-1''-Hydroxy-2''-Propylamide endogenous fatty acid amide with inhibitory effects on pro-inflammatory mediators (NO, IL-1β, IL-6, and TNF-α). (R)-(+)-Docosahexaenyl-1''-Hydroxy-2''-Propylamide is a homolog of

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide synthesis

35320-23-1
81926-94-5
6217-54-5
1282618-08-9
Synthesis of (4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide from (R)-(-)-2-Amino-1-propanol and ETHYLDOCOSAHEXAENOATE

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide Preparation Products And Raw materials

Raw materials

Preparation Products

(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3770 55
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 28091 58
SHANGHAI ZZBIO CO., LTD. 13916577892 19921389125 tech@zzbioco.com China 12063 58
Supplier Advantage
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Shanghai Hongye Biotechnology Co. Ltd 58
Energy Chemical 58
MedBioPharmaceutical Technology Inc 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
SHANGHAI ZZBIO CO., LTD. 58
(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(2R)-1-hydroxypropan-2-yl]docosa-4,7,10,13,16,19-hexaenamide (R)-(+)-Docosahexaenyl-1&rsquo 4,7,10,13,16,19-Docosahexaenamide, N-[(1R)-2-hydroxy-1-methylethyl]-, (4Z,7Z,10Z,13Z,16Z,19Z)- (R)-(+)-Docosahexaenyl-1'-Hydroxy-2'-Propylamide 1282618-08-9