ANTI-MAD-3
- CAS No.
- Chemical Name:
- ANTI-MAD-3
- Synonyms
- Anti-MGA1;Anti-IFCR;Anti-IKBA;Anti-IκBα;Anti-gp280;Anti-Iκbns;ANTI-MAD-3;Anti-NFKBI;Anti-bHLHc13;Anti-PRO0082
- CBNumber:
- CB4461908
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD01633603
- MOL File:
- Mol file
ANTI-MAD-3 price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4300440 | Anti-NFKBIA (Ab-42) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300125 | Anti-phospho-NFKBIA (pSer32/pSer36) antibody produced in rabbit affinity isolated antibody | 100μG | $511 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB2501645 | Anti-MXD3 (C-terminal) antibody produced in goat affinity isolated antibody, buffered aqueous solution | 100μg | $568 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB1411059 | Anti-CSGALNACT2 antibody produced in rabbit purified immunoglobulin, buffered aqueous solution | 100μG | $524 | 2024-03-01 | Buy | |
| Sigma-Aldrich | HPA029207 | Anti-NFKBIA antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution | 100μL | $514 | 2024-03-01 | Buy |
ANTI-MAD-3 Chemical Properties,Uses,Production
Uses
Rabbit Anti-NFKBIB (AB1) can be used for western blot (5 μg/ml) and IHC (4-8 μg/ml) assays.
General Description
NFKBIB is an NF-κB inhibitor that forms a complex with NF-κB and traps it in the cytoplasm. Serine phosphorylation in NFKBIB proteins activates its ubiquitin-mediated degradation. This subsequently facilitates the nuclear transport and functions of NF-κB proteins.
Rabbit Anti-NFKBIB antibody recognizes human, mouse, rat, canine, and bovine NFKBIB.
Biochem/physiol Actions
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM].NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM].
ANTI-MAD-3 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-MAD-3 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Dongguan Biaobiao Experimental Equipment Technology Co., Ltd. | -- | CHINA | 6673 | 58 | |
| Beijing Bai Ao Si Biotechnology Co., Ltd. | -- | yangmei@bioneeds.net | CHINA | 6999 | 58 |
| Guangzhou Weijia Technology Co., Ltd. | -- | WHIGA22@126.COM | CHINA | 6748 | 58 |
| Beijing Xiangsheng Xingye Technology Co., Ltd. | -- | xs_bio@163.com | CHINA | 5130 | 58 |
| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
| Riedel-de Haen AG | -- | United States | 6825 | 87 | |
| BD Biosciences | -- | United States | 5013 | 82 |