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(S)-KT109

(S)-KT109 Structure
(S)-KT109 structure
CAS No.
2055172-61-5
Chemical Name:
(S)-KT109
Synonyms
(S)-KT109;(S)KT109,(S) KT109,(S)-KT-109;(4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone;Methanone, (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-
CBNumber:
CB44665636
Molecular Formula:
C27H26N4O
Molecular Weight:
422.52
MDL Number:
MOL File:
2055172-61-5.mol
Last updated:2023-05-21 10:59:17
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(S)-KT109 Properties

Boiling point 637.3±53.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 10 mg/mL; DMSO: 10 mg/mL
form A crystalline solid
pka -1.02±0.70(Predicted)

(S)-KT109 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 25683 (S)-KT109 ≥98% 2055172-61-5 500μg $93 2024-03-01 Buy
Cayman Chemical 25683 (S)-KT109 ≥98% 2055172-61-5 1mg $176 2024-03-01 Buy
AK Scientific 9945EC [(2S)-2-Benzylpiperidin-1-yl]-[4-(4-phenylphenyl)triazol-1-yl]methanone 2055172-61-5 1mg $293 2021-12-16 Buy
Product number Packaging Price Buy
25683 500μg $93 Buy
25683 1mg $176 Buy
9945EC 1mg $293 Buy

(S)-KT109 Chemical Properties,Uses,Production

Description

(S)-KT109 is the (S) isomer of the diacylglycerol lipase β (DAGLβ) inhibitor KT109 .1 (S)-KT109 is a less potent inhibitor of DAGLβ (IC50 = 39.81 nM), DAGLα-mediated hydrolysis of 1-stearoyl-2-arachidonoyl-sn-glycerol (IC50 = 794.3 nM), and α/β-hydrolase domain-containing protein 6 (ABHD6; IC50 = 630.9 nM) than (R)-KT109 .

References

1. Deng, H., Kooijman, S., van den Nieuwendijk, A.M.C.H., et al. Triazole ureas act as diacylglycerol lipase inhibitors and prevent fasting-induced refeeding J. Med. Chem. 60(1),428-440(2017).

(S)-KT109 Preparation Products And Raw materials

Raw materials

Preparation Products

(S)-KT109 Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 18470 58
Supplier Advantage
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
(S)-KT109 (S)KT109,(S) KT109,(S)-KT-109 Methanone, (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]- (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[(2S)-2-(phenylmethyl)-1-piperidinyl]-methanone 2055172-61-5