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1-Methylpiperazine

1-Methylpiperazine Structure
1-Methylpiperazine structure
CAS No.
109-01-3
Chemical Name:
1-Methylpiperazine
Synonyms
N-METHYLPIPERAZINE;methylpiperazine;NMPRZ;4-Methylpiperazine;N-Methylpiperazin;Piperazine,1-methyl-;CL046;AKOS BBS-00003665;1-methyl-piperazin;1-METHYLPIPERAZINE
CBNumber:
CB4478526
Molecular Formula:
C5H12N2
Molecular Weight:
100.16
MDL Number:
MFCD00005966
MOL File:
109-01-3.mol
MSDS File:
SDS
Last updated:2024-11-22 13:59:06
Request For Quotation

1-Methylpiperazine Properties

Melting point -6 °C
Boiling point 138 °C(lit.)
Density 0.903 g/mL at 25 °C(lit.)
vapor density 3.5 (vs air)
vapor pressure 12 hPa (20 °C)
refractive index n20/D 1.466(lit.)
Flash point 108 °F
storage temp. 2-8°C
solubility Chloroform (Soluble), Methanol (Soluble)
pka pK1:4.94(+2);pK2:9.09(+1) (25°C,μ=0.1)
form Liquid
color Clear
Specific Gravity 0.903
PH 11-12 (50g/l, H2O, 20℃)
explosive limit 1.2-9.9%(V)
Viscosity 2.27mm2/s
Water Solubility soluble
Sensitive Hygroscopic
BRN 102724
InChIKey PVOAHINGSUIXLS-UHFFFAOYSA-N
LogP -0.57 at 25℃
CAS DataBase Reference 109-01-3(CAS DataBase Reference)
FDA UNII B92I95EL9Q
NIST Chemistry Reference Piperazine, 1-methyl-(109-01-3)
EPA Substance Registry System Piperazine, 1-methyl- (109-01-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H226-H312-H314-H331
Precautionary statements  P210-P260-P280-P304+P340+P310-P305+P351+P338-P370+P378
Hazard Codes  T,F,C,Xi
Risk Statements  10-21-23-34-36/37/38-20/21
Safety Statements  16-26-36/37/39-45-36
RIDADR  UN 2734 8/PG 2
WGK Germany  2
RTECS  TM1225000
Autoignition Temperature 320 °C
Hazard Note  Flammable/Toxic/Corrosive/Store under nitrogen
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29335995
Toxicity LD50 orally in Rabbit: 2547 mg/kg LD50 dermal Rabbit 1341 mg/kg
NFPA 704
2
2 0

1-Methylpiperazine price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.05859 1-Methylpiperazine for synthesis 109-01-3 5ml $35 2024-03-01 Buy
Sigma-Aldrich BP1118 1-Methylpiperazine British Pharmacopoeia (BP) Reference Standard 109-01-3 15MG $229 2024-03-01 Buy
Sigma-Aldrich 8.05859 1-Methylpiperazine for synthesis 109-01-3 250ML $120 2024-03-01 Buy
Sigma-Aldrich 130001 1-Methylpiperazine 99% 109-01-3 5g $36.5 2024-03-01 Buy
Sigma-Aldrich 14549 1-Methylpiperazine analytical standard 109-01-3 5ml $70.8 2024-03-01 Buy
Product number Packaging Price Buy
8.05859 5ml $35 Buy
BP1118 15MG $229 Buy
8.05859 250ML $120 Buy
130001 5g $36.5 Buy
14549 5ml $70.8 Buy

1-Methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

clear liquid

Uses

1-Methylpiperazine is used in the preparation of 2-(4-methyl-1-piperazinylmethyl)acrylophenone. It is involved in the preparation of 1-(4-methoxy-phenyl)-4-methyl-piperazine by reacting with 1-chloro-4-methoxy-benzene. It acts as an intermediate in the synthesis of active pharmaceutical ingredients like ofloxacin, rifampicin, clozapine, sildenafil, trifluoperazine and zopiclone. Further, it is used as a mimic template in the preparation of molecularly imprinted microspheres. In addition to this, it is used in the generation of difunctional strong anion-exchange stationary phase from a 1,4-diazacyclohexane derivative.

Uses

1-Methylpiperazine is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP)

Definition

ChEBI: 1-Methylpiperazine is a N-methylpiperazine.

Hazard

Moderate fire risk.

Flammability and Explosibility

Flammable

Safety Profile

Poison by intraperitoneal route. Moderately toxic by inhalation, ingestion, and skin contact. A severe skin and eye irritant. Flammable liquid when exposed to heat or flame; can react with oxidizing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

1-Methylpiperazine synthesis

16339-07-4
109-01-3
6928-85-4
Synthesis of 1-Methylpiperazine from 1-methyl-4-nitrosopiperazine

1-Methylpiperazine Preparation Products And Raw materials

Raw materials

PIPERAZINE DIHYDROCHLORIDE PIPERAZINE HEXAHYDRATE Carbon dioxide Piperazine Methanol

Preparation Products

AZIMILIDE 3-(4-Methylpiperazin-1-yl)aniline 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbaldehyde 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbonitrile 1-Amino-4-methylpiperazine
Zopiclone 1-METHYLPIPERAZINE DIHYDROCHLORIDE 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonyl chloride 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanamine
3-(4-Methylpiperazin-1-ylmethyl)benzoic acid 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxylic acid 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carbonitrile Chlorcyclizine hydrochloride Levofloxacin
(3,4-DIAMINO-PHENYL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 2-(4-Methylpiperazin-1-yl)pyrimidine-5-carboxamide (2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)methanol Ethyl 2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxylate 3-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZALDEHYDE
(4-METHYL-PIPERAZIN-1-YL)-ACETIC ACID Ethyl 2-(4-methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate 3-Hydrazinyl-1-(4-methylpiperazin-1-yl)propan-1-one CHLORCYCLIZINE 2-(4-Methylpiperazin-1-yl)pyrimidin-5-amine
1-AdaMantanethylaMine 1-FORMYL-4-METHYLPIPERAZINE 4-(4-METHYLPIPERAZINOMETHYL)BENZOIC ACID (2-(4-Methylpiperazin-1-yl)pyrimidin-5-yl)methanol 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carbaldehyde
Clozapine 1-METHYL-4-(3-NITROPHENYL)PIPERAZINE 4-[(4-Methylpiperazin-1-yl)methyl]aniline 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylic acid 2-(4-Methylpiperazin-1-yl)-6-(trifluoromethyl)pyrimidin-4-amine
4-(4-Methylpiperazino)aniline 1-METHYL-4-(4-NITROPHENYL)PIPERAZINE 2-Hydrazinyl-1-(4-methylpiperazin-1-yl)ethanone 1-METHYL-4-(4-NITROBENZYL)PIPERAZINE 1-methyl-4-nitrosopiperazine

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1-Methylpiperazine Suppliers

Global( 771)Suppliers
Supplier Tel Email Country ProdList Advantage
Shandong Believe Chemical PTE.LTD
+86-18553607090 +8618553607090 1093908296@qq.com China 1667 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8812 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5857 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-13131129325 sales1@chuanghaibio.com China 5893 58
Sinoway Industrial co., ltd. 		0592-5800732; +8613806035118 xie@china-sinoway.com China 988 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
Hebei Mojin Biotechnology Co.,Ltd 		+86-15028179902 angelia@hbmojin.com China 1177 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Supplier Advantage
Shandong Believe Chemical PTE.LTD
58
Hebei Weibang Biotechnology Co., Ltd 		58
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Sinoway Industrial co., ltd. 		58
Henan Fengda Chemical Co., Ltd 		58
Hebei Mojin Biotechnology Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60

Related articles

View Lastest Price from 1-Methylpiperazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Methylpiperazine pictures 2024-11-22 1-Methylpiperazine
109-01-3
 US $0.00 / Kg/Bag 2Kg/Bag 99% up, High Density 20 tons Sinoway Industrial co., ltd.
1-Methylpiperazine pictures 2024-11-22 1-Methylpiperazine
109-01-3
 US $10.00 / kg 1kg 99% 10 mt Hebei Weibang Biotechnology Co., Ltd
1-Methylpiperazine pictures 2024-11-21 1-Methylpiperazine
109-01-3
 US $5.00 / kg 1kg ≥98% 500mt/year Jinan Finer Chemical Co., Ltd
  • 1-Methylpiperazine pictures
  • 1-Methylpiperazine
    109-01-3
  • US $0.00 / Kg/Bag
  • 99% up, High Density
  • Sinoway Industrial co., ltd.

1-Methylpiperazine Spectrum

1-Methylpiperazine(109-01-3)MS1-Methylpiperazine(109-01-3)1HNMR1-Methylpiperazine(109-01-3)13CNMR1-Methylpiperazine(109-01-3)IR11-Methylpiperazine(109-01-3)IR21-Methylpiperazine(109-01-3)Raman

109-01-3(1-Methylpiperazine)Related Search:

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Tribenuron methyl Methyl 4-Chloromethyl-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide

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1-methyl-piperazin 1-METHYLPIPERAZINE FOR SYNTHESIS Cyclizine Related CoMpound A N-Methyl piperazine 1-Methylpiperazine, 99+% 100GR 1-Methylpiperazine, 99+% 500GR 1-Methylpiperazine, 99+% 5GR LABOTEST-BB LTBB000517 METHYLPIPERAZINE-N 1-METHYLPIPERAZINE AKOS BBS-00003665 1-METHYLPIPERAZINE, STANDARD FOR GC N-MethylPiperazineForSynthesis N-EthylPiperazineForSynthesis N-Methylpiperazine, 98+% 1-Methylpiperazine, 99+% n-METHYL PIPERAZINE extrapure 1-Methylpiperazine, 98+% Olanzapine Impurity 15 CL046 1-Methylpiperazine / N-Methylpiperazine 1-Methylpiperazine> Cyclizine impurity A CRS Diethylcarbamazine EP Impurity A Imatinib EP Impurity G N-Methylpiperazini N-METHYL PIPERASINE 1-Methylpiperazine ISO 9001：2015 REACH 1-Methylpiperazine extrapure, 99% Cyclizine impurity A (Y0000886) Cyclizine Related Compound A (1-methylpiperazine) (1154015) N-METHYLPIPERAZINE NMPRZ 4-Methylpiperazine methylpiperazine N-Methylpiperazin Piperazine,1-methyl- Cyclizine USP Related Compound A Imatinib Mesilate EP Impurity G Imatinib Impurity 54 Cyclizine Hydrochloride Impurity A Imatinib Mesilate Impurity G Chlorcyclizine EP Impurity A 4-((3-carboxy-2-hydroxynaphthalen-1-yl)methyl)-3-hydroxy-7-methyl-2-naphthoic acid N-Methyl Piperazine 99% For Synthesis N-Methyl Peprazine 1-Methyipiperazine 109-01-3 1109-01-3 203-639-5 468-79-0 NC4H8NCH3 AMINE Building Blocks Analytical Standards Analytical Chromatography Product Catalog Alphabetic Piperazines