AR-C 66096 tetrasodium salt
- CAS No.
- 145782-74-7
- Chemical Name:
- AR-C 66096 tetrasodium salt
- Synonyms
- CBNumber:
- CB44806431
- Molecular Formula:
- C14H23F2N5NaO12P3S
- Molecular Weight:
- 639.33
- MDL Number:
- MOL File:
- 145782-74-7.mol
AR-C 66096 tetrasodium salt price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A766568 | AR-C66096TetrasodiumSalt | 145782-74-7 | 1mg | $340 | 2021-12-16 | Buy |
ApexBio Technology | B5408 | AR-C66096tetrasodiumsalt | 145782-74-7 | 1mg | $549 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008925 | AR-C 66096 TETRASODIUM SALT 95.00% | 145782-74-7 | 1MG | $787.5 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0008925 | AR-C 66096 TETRASODIUM SALT 95.00% | 145782-74-7 | 5MG | $2373.91 | 2021-12-16 | Buy |
AR-C 66096 tetrasodium salt Chemical Properties,Uses,Production
Biological Activity
the platelet p2t receptor plays a major role in platelet aggregation, and its antagonists are suggested to have significant therapeutic potential as antithrombotic agents. ar-c 66096 is a novel, potent and selective antagonist at human platelet p2t-purinoceptors.
in vitro
in suspensions of human washed platelets, ar-c 66096 (1-100 nm) produced concentrationdependent rightward displacement of concentration-effect (e/[a]) curves obtained for adp-induced platelet aggregation. the anti-aggregatory potency of ar-c 66096 was not influenced by increasing the incubation time from 2 to 15 min nor by inclusion of the p1-purinoceptor antagonist 8-sulphophenyltheophylline at a concentration (300 μm) [1].
in vivo
ar-c 66096 behaved as a weak (pa50 3.68) but full p2x-purinoceptor agonist in preparations of the isolated rabbit ear artery and as a weak, competitive antagonist (apparent pkb 4.71) at p2y-purinoceptors in the isolated guinea-pig aorta, indicating a selectivity of at least 9000 fold for the pzrsubtype. in the latter preparation, non-specific relaxations were observed by concentrations of ar-c 66096 >10 μm [1].
storage
Store at -20°C
References
[1] humphries, r. g.; tomlinson, w.; ingall, a. h.; cage, p. a.; leff, p. fpl 66096: a novel, highly potent and selective antagonist at human platelet p2t-purinoceptors. br. j. pharmacol. 1994, 113, 1057-1063.
AR-C 66096 tetrasodium salt Preparation Products And Raw materials
Raw materials
Preparation Products
AR-C 66096 tetrasodium salt Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4552 | 58 |
ApexBio Technology | -- | sales@apexbt.com | United States | 6254 | 58 |
Supplier | Advantage |
---|---|
Aladdin Scientific | 58 |
Nanjing Meihao Pharmaceutical Technology Co., Ltd. | 58 |
BOC Sciences | 65 |
Nantong QuanYi Biotechnology Co., Ltd | 58 |
ApexBio Technology | 58 |