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KAI407
- CAS No.
- 1513879-18-9
- Chemical Name:
- KAI407
- Synonyms
- KAI407;KAI407;KAI-407;KAI 407;Imidazo[1,2-a]pyrazine-6-carboxamide, N-(4-cyanophenyl)-N-methyl-3-[4-(trifluoromethyl)phenyl]-
- CBNumber:
- CB44844954
- Molecular Formula:
- C22H14F3N5O
- Molecular Weight:
- 421.37
- MDL Number:
- MOL File:
- 1513879-18-9.mol
Last updated:2024-10-23 13:36:13
KAI407 Chemical Properties,Uses,Production
Description
KAI407 is a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. KAI407 showed an activity profile similar to that of primaquine (PQ), efficiently killing the earliest stages of the parasites that become either primary hepatic schizonts or hypnozoites (50% inhibitory concentration [IC50] for hypnozoites, KAI407, 0.69 μM, and PQ, 0.84 μM; for developing liver stages, KAI407, 0.64 μM, and PQ, 0.37 μM). KAI407 may represent a new compound class for P. vivax malaria prophylaxis and potentially a radical cure.
KAI407 Preparation Products And Raw materials
Raw materials
Preparation Products
KAI407 Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19863 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9410 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19711 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| DC Chemicals | 58 |
| TargetMol Chemicals Inc. | 58 |
KAI407
KAI407;KAI-407;KAI 407
Imidazo[1,2-a]pyrazine-6-carboxamide, N-(4-cyanophenyl)-N-methyl-3-[4-(trifluoromethyl)phenyl]-
1513879-18-9