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BAY-218

BAY-218 Structure
BAY-218 structure
CAS No.
2162982-11-6
Chemical Name:
BAY-218
Synonyms
CPD3504;BAY-218;BAY-2335218;AHR antagonist 1;BAY-218, 10 mM in DMSO;BAY-218(AHR antagonist 1);BAY2335218;BAY-2335218;BAY 2335218;BAY218;BAY 218;BAY-218;6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(1S)-2-hydroxy-1-methyl-ethyl]-3-oxo-pyridazine-4-carboxamide;(S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2，3-dihydropyridazine-4-carboxamide;6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-3-oxo-2,3-dihydropyridazine-4-carboxamide
CBNumber:
CB44908494
Molecular Formula:
C20H17ClFN3O3
Molecular Weight:
401.82
MDL Number:
MOL File:
2162982-11-6.mol
Last updated:2025-04-17 18:22:24
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BAY-218 Properties

Density 1.37±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:80.0(Max Conc. mg/mL);199.09(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);49.77(Max Conc. mM)
form Solid
pka 11.81±0.20(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

BAY-218 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0040922 AHRantagonist1 99.07% 2162982-11-6 5mg $100 2021-12-16 Buy
ChemScene CS-0040922 AHRantagonist1 99.07% 2162982-11-6 10mg $150 2021-12-16 Buy
ChemScene CS-0040922 AHRantagonist1 99.07% 2162982-11-6 25mg $290 2021-12-16 Buy
ChemScene CS-0040922 AHRantagonist1 99.07% 2162982-11-6 50mg $490 2021-12-16 Buy
ChemScene CS-0040922 AHRantagonist1 99.07% 2162982-11-6 100mg $850 2021-12-16 Buy
Product number Packaging Price Buy
CS-0040922 5mg $100 Buy
CS-0040922 10mg $150 Buy
CS-0040922 25mg $290 Buy
CS-0040922 50mg $490 Buy
CS-0040922 100mg $850 Buy

BAY-218 Chemical Properties,Uses,Production

Uses

BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses[1].

in vivo

BAY-218 (example 23) (p.o; 30 mg/kg; bid) has good anti-tumor effect combinated with aPD-L1[1].

Animal Model:Balb/c mice (subcutaneously CT26 cells)[1]
Dosage:30 mg/kg
Administration:p.o, bid
Result:Significantly decreased tumors size combinated with aPD-L1.

References

[1] Norbert Schmees, et al. 3-oxo-2,6-diphenyl-2,3-dihydropyridazine-4-carboxamides. WO2017202816A1.

BAY-218 Preparation Products And Raw materials

Raw materials

Preparation Products

BAY-218 Suppliers

Global( 70)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32222 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10473 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 24727 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38642 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 5221 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
BOC Sciences 		58
TargetMol Chemicals Inc. 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
InvivoChem 		58
LEAP CHEM CO., LTD. 		58
TargetMol Chemicals Inc. 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Aladdin Scientific 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58

View Lastest Price from BAY-218 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAY-218 pictures 2024-11-19 BAY-218
2162982-11-6
 US $34.00-66.00 / mg 99.85% 10g TargetMol Chemicals Inc.
  • BAY-218 pictures
  • BAY-218
    2162982-11-6
  • US $34.00-66.00 / mg
  • 99.85%
  • TargetMol Chemicals Inc.

BAY-218 Spectrum

BAY-218(2162982-11-6)1HNMR
BAY2335218;BAY-2335218;BAY 2335218;BAY218;BAY 218;BAY-218 BAY-218 CPD3504 BAY-2335218 AHR antagonist 1 4-Pyridazinecarboxamide, 6-(4-chlorophenyl)-2-(3-fluorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-3-oxo- 6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(2S)-1-hydroxypropan-2-yl]-3-oxo-2,3-dihydropyridazine-4-carboxamide (S)-6-(4-Chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2，3-dihydropyridazine-4-carboxamide BAY-218(AHR antagonist 1) cancer,human monocytic U937 cells,AHR antagonist1,inhibit,Aryl Hydrocarbon Receptor,Inhibitor,BAY218,aryl hydrocarbon receptor (AHR),U87 glioblastoma cells,AHR antagonist-1,immune,BAY 218,BAY-218,AhR 6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-[(1S)-2-hydroxy-1-methyl-ethyl]-3-oxo-pyridazine-4-carboxamide BAY-218, 10 mM in DMSO 2162982-11-6