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FR-194921

FR-194921 Structure
FR-194921 structure
CAS No.
202646-80-8
Chemical Name:
FR-194921
Synonyms
FR-194921;FR194921 >=98% (HPLC);3(2H)-Pyridazinone, 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-
CBNumber:
CB44919742
Molecular Formula:
C23H23N5O
Molecular Weight:
385.46
MDL Number:
MFCD27965870
MOL File:
202646-80-8.mol
Last updated:2025-01-27 09:38:02
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FR-194921 Properties

Density 1.29±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 2mg/mL, clear (warmed)
pka 8.51±0.10(Predicted)
form Solid
color Off-white to light yellow
FDA UNII 9765J8QB7Q
UNSPSC Code 12352200
NACRES NA.77

FR-194921 Chemical Properties,Uses,Production

Biological Activity

FR194921 is a blood-brain barrier-permeable A1R adenosine receptor antagonist. The measured Ki values of FR194921 for the human adenosine A1 receptors have been in the low nM range with no binding affinity for A2A and A3 receptors up to 1μM. It is orally active and has good bioavailability. FR194921 was used in a recent study to restore auditory cortex plasticity. Paired with sound exposure, FR194921 resulted in cortical map plasticity and improved auditory perception in adult mice.

FR-194921 Preparation Products And Raw materials

Raw materials

Preparation Products

FR-194921 Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44807 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Energy Chemical 58
TargetMol Chemicals Inc. 58

View Lastest Price from FR-194921 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FR-194921 pictures 2024-10-28 FR-194921
202646-80-8
 US $1520.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • FR-194921 pictures
  • FR-194921
    202646-80-8
  • US $1520.00-1980.00 / mg
  • TargetMol Chemicals Inc.
FR-194921 FR194921 >=98% (HPLC) 3(2H)-Pyridazinone, 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)- 202646-80-8