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ZEBULARINE

ZEBULARINE structure

CAS No.: 3690-10-6

Chemical Name:: ZEBULARINE

Synonyms: NSC 309132;4-Deoyuridine;4-Deoxyuridine;Zebularine Zebularine;Zebularine (NSC309132;NSC309132;4-DEOXYURIDINE;4-Deoyuridine,Zebularine;Zebularine, 10 mM in DMSO;2-Pyrimidone-1-β-D-riboside;Uridine Impurity 23 (Zebularine)

CBNumber:: CB4497499

Molecular Formula:: C9H12N2O5

Molecular Weight:: 228.2

MDL Number:: MFCD04973699

MOL File:: 3690-10-6.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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ZEBULARINE Properties

Melting point	160-162?C
Boiling point	499.0±55.0 °C(Predicted)
Density	1.73±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 16 mg/mL, soluble
form	solid
pka	13.48±0.70(Predicted)
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
InChIKey	RPQZTTQVRYEKCR-WCTZXXKLSA-N
FDA UNII	7A9Y5SX0GY
UNSPSC Code	12352203
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H320-H335
Precautionary statements	P264-P270-P301+P312-P330
WGK Germany	3
RTECS	UW7539720
HS Code	2934999090

ZEBULARINE price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	691400	Zebularine	3690-10-6	10mg	$216	2024-03-01	Buy
Sigma-Aldrich	691400	Zebularine	3690-10-6	25mg	$475	2024-03-01	Buy
TCI Chemical	Z0022	Zebularine >98.0%(HPLC)(T)	3690-10-6	200mg	$193	2024-03-01	Buy
TCI Chemical	Z0022	Zebularine >98.0%(HPLC)(T)	3690-10-6	1g	$571	2024-03-01	Buy
Cayman Chemical	10975	Zebularine ≥98%	3690-10-6	1mg	$26	2024-03-01	Buy

Product number	Packaging	Price	Buy
691400	10mg	$216	Buy
691400	25mg	$475	Buy
Z0022	200mg	$193	Buy
Z0022	1g	$571	Buy
10975	1mg	$26	Buy

ZEBULARINE Chemical Properties,Uses,Production

Description

Zebularine (3690-10-6) is an orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Zebularine inhibits cytidine deaminase (Ki ~ 2 μM and; induces differentiation of mesenchymal stem cells into cardiomyocytes.

Chemical Properties

White Solid

Uses

It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.

Definition

ChEBI: Zebularine is a member of pyrimidine ribonucleosides.

Biological Activity

Orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC 50 = 120 μ M) and re-activates silenced genes in T24 bladder carcinoma cells. Also inhibits cytidine deaminase (K i ~ 2 μ M).

Biochem/physiol Actions

Zebularine is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.

storage

Desiccate at RT

ZEBULARINE Preparation Products And Raw materials

Raw materials

Preparation Products

ZEBULARINE Suppliers

Global( 130)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	laboratory@coreychem.com	China	30230	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3927	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19552	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32222	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9642	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	9985	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
Wuhu Nuowei chemistry Co., Ltd.	+86-0553-2911116-802 +86-18055311600	sales1@nuowei-chem.com	China	1638	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

Supplier	Advantage
Career Henan Chemica Co	58
Shaanxi Dideu Medichem Co. Ltd	58
Shenzhen Nexconn Pharmatechs Ltd	58
BOC Sciences	58
TargetMol Chemicals Inc.	58
Finetech Industry Limited	58
NewCan Biotech Limited	58
InvivoChem	58
Wuhu Nuowei chemistry Co., Ltd.	58
LEAPCHEM CO., LTD.	58

View Lastest Price from ZEBULARINE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	Zebularine 3690-10-6	US $38.00-127.00 / mg		99.84%	10g	TargetMol Chemicals Inc.
	2024-07-20	ZEBULARINE 3690-10-6	US $1.00 / Kg	1Kg	98%	20T	Shaanxi Dideu Medichem Co. Ltd

Zebularine
3690-10-6
US $38.00-127.00 / mg
99.84%
TargetMol Chemicals Inc.

ZEBULARINE
3690-10-6
US $1.00 / Kg
98%
Shaanxi Dideu Medichem Co. Ltd

ZEBULARINE Spectrum

ZEBULARINE(3690-10-6)¹HNMR

3690-10-6(ZEBULARINE)Related Search:

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1of4

4-Deoyuridine 1-b-D-ribofuranosyl-2-(1H)-pyriMidinone anticancer drug, DNA Methylation inhibitor 2(1H)-Pyrimidinone, 1-β-D-ribofuranosyl- 2-Pyrimidone-1-β-D-riboside 1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone Pyrimidin-2-one beta-D-ribofuranoside 1-(β-d-ribofuranosyl)-1,2-dihydropyrimidin-2-one pyrimidin-2-one beta-ribofuranoside 1--D-Ribofuranosyl-2(1H)-pyrimidinone 4-Deoxyuridine NSC 309132 Pyrimidin-2-one -D-Ribofuranoside 1-(β-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one, 2-Pyrimidone-1-β-D-riboside 2(1H)-PyriMidinone, 1-b-D-ribofuranosyl- Zebularine Zebularine Uridine Impurity 23 (Zebularine) 4-Deoyuridine, 1-beta-D-ribofuranosyl-2-(1H)-pyrimidinone Zebularine (NSC309132 2-HYDROXY-PYRIMIDINE-1-B-D-RIBOSIDE Zebularine - CAS 3690-10-6 - Calbiochem NSC309132;4-DEOXYURIDINE 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one 1-beta-D-Ribofuranosyl -l ,2-dihydropyrimidin-2-one NSC 309132,NSC-309132,DNMTs,Inhibitor,DNA MTases,Autophagy,Zebularine,DNA Methyltransferase,inhibit 4-Deoyuridine,Zebularine 2(1H)-Pyrimidinone, 1-beta-D-ribofuranosyl- Zebularine, DNA methyltransferase (DNMT) inhibitor Zebularine, 10 mM in DMSO 3690-10-6 Carbohydrates & Derivatives Inhibitors Intermediates & Fine Chemicals Pharmaceuticals