19R(20S)-EpDPA
- CAS No.
- 2242542-60-3
- Chemical Name:
- 19R(20S)-EpDPA
- Synonyms
- 19R(20S)-EpDPA;4,7,10,13,16-Octadecapentaenoic acid, 18-[(2R,3S)-3-ethyl-2-oxiranyl]-, (4Z,7Z,10Z,13Z,16Z)-
- CBNumber:
- CB46197649
- Molecular Formula:
- C22H32O3
- Molecular Weight:
- 344.49
- MDL Number:
- MOL File:
- 2242542-60-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS02 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| NFPA 704 |
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19R(20S)-EpDPA Chemical Properties,Uses,Production
Biological Activity
19R(20S)-EpDPA is an oxylipin and a metabolite of docosahexaenoic acid .1,2 It is formed from DHA by various cytochrome P450 (CYP) isoforms in a stereoselective manner.2 19R(20S)-EpDPA (30 nM) prevents calcium-induced increases in the spontaneous beating of isolated neonatal rat cardiomyocytes (NRCMs).3
References
1.Cinelli, M.A., Yang, J., Scharmen, A., et al.Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acidsJ. Lipid Res.59(11)2237-2252(2018) 2.Lucas, D., Goulitquer, S., Marienhagen, J., et al.Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450J. Lipid Res.51(5)1125-1133(2010) 3.Burke, J.E., and Dennis, E.A.Phospholipase A2 structure/function, mechanism, and signalingJ. Lipid Res.50(Suppl)S237-S242(2009)
19R(20S)-EpDPA Preparation Products And Raw materials
Raw materials
Preparation Products
19R(20S)-EpDPA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8739 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28118 | 58 |
| Supplier | Advantage |
|---|---|
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |