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9(E),11(E)-12-nitro Conjugated Linoleic Acid

CAS No.
1515620-30-0
Chemical Name:
9(E),11(E)-12-nitro Conjugated Linoleic Acid
Synonyms
9(E),11(E)-12-nitro Conjugated Linoleic Acid;9,11-Octadecadienoic acid, 12-nitro-, (9E,11E)-
CBNumber:
CB46198000
Molecular Formula:
C18H31NO4
Molecular Weight:
325.44
MDL Number:
MOL File:
1515620-30-0.mol
Last updated:2023-06-08 09:03:09

9(E),11(E)-12-nitro Conjugated Linoleic Acid Properties

Boiling point 457.6±18.0 °C(Predicted)
Density 1.016±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 1mg/mL,DMF: 50mg/mL,DMSO: 50mg/mL,Ethanol: 50mg/mL
pka 4.78±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

9(E),11(E)-12-nitro Conjugated Linoleic Acid Chemical Properties,Uses,Production

Biological Activity

9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1 It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .2 9(E),11(E)-12-nitro CLA has been found in human plasma.

References

1.Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014) 2.Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012)

9(E),11(E)-12-nitro Conjugated Linoleic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

9(E),11(E)-12-nitro Conjugated Linoleic Acid Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
ChemeGen 中国 18818260767 sales@chemegen.com China 6975 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24647 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11975 58
SHANGHAI ZZBIO CO., LTD. 15102117276 19921389125 tech@zzbioco.com China 12064 58
9(E),11(E)-12-nitro Conjugated Linoleic Acid 9,11-Octadecadienoic acid, 12-nitro-, (9E,11E)- 1515620-30-0