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UNCARINE E

CAS No.
5171-37-9
Chemical Name:
UNCARINE E
Synonyms
UNCARINE E;Uncarine E-RM;ISOPTEROPODINE;7-Isopteropodine;Rhynchophylline E;allo-Isopteropodine;Isopteropodine (20 mg);Uncarine E,Isopteropodine;Isopteropodine(Uncarine E);(7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
CBNumber:
CB4676247
Molecular Formula:
C21H24N2O4
Molecular Weight:
368.43
MDL Number:
MFCD03788766
MOL File:
5171-37-9.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:13

UNCARINE E Properties

Melting point 209-211 °C
Boiling point 555.2±50.0 °C(Predicted)
Density 1.33
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
pka 13.56±0.60(Predicted)
form Solid
color Pale Yellow to Pale Beige
FDA UNII J9IZ1U593L

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310-P321-P330-P405-P501
HS Code  2939800000

UNCARINE E price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89816 Uncarine E phyproof? Reference Substance 5171-37-9 10MG $584 2024-03-01 Buy
Sigma-Aldrich 1351107 Isopteropodine United States Pharmacopeia (USP) Reference Standard 5171-37-9 20MG $1070 2024-03-01 Buy
TRC I874220 Isopteropodine 5171-37-9 25mg $730 2021-12-16 Buy
TRC I874220 Isopteropodine 5171-37-9 10mg $305 2021-12-16 Buy
ChemScene CS-0032252 Isopteropodine 5171-37-9 5mg $343 2021-12-16 Buy
Product number Packaging Price Buy
PHL89816 10MG $584 Buy
1351107 20MG $1070 Buy
I874220 25mg $730 Buy
I874220 10mg $305 Buy
CS-0032252 5mg $343 Buy

UNCARINE E Chemical Properties,Uses,Production

Description

This alkaloid occurs in several species of Uncaria and yields colourless crystals from MeOH. It is laevorotatory with [α]D - 96° (CHCI3). The structure has been determined by spectroscopic methods.

Uses

Isopteropodine is an alkaloid extract from Uncaria Tomentosathat is believed to possess antiproliferative and pro-apoptotic effects.

Definition

ChEBI: Uncarine E is a member of indolizines.

References

Hart, Johns, Lamberton., Chem. Commun., 87 (1967)
Hemingway, Phillipson., 1. Pharm. Pharmacol., 24, 169P (1972)

UNCARINE E Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 80)Suppliers
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allo-Isopteropodine UNCARINE E (7alpha,19alpha,20alpha)-19-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester ISOPTEROPODINE (7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester 7-Isopteropodine (1R,4aR,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester methyl (1R,4aR,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate methyl (1R,4aR,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate Isopteropodine (20 mg) Isopteropodine(Uncarine E) Rhynchophylline E Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aS)- (1'S,3S,4a'S,5a'S,10a'S)-methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate Uncarine E,Isopteropodine (1'S,3S,4a'S,5a'S,10a'S)-Methyl 1'-methyl-2-oxo-1',4a',5',5a',7',8',10',10a'-octahydrospiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate Uncarine E-RM 5171-37-9 standard material,plant extracts