ChemicalBook >> CAS DataBase List >>2-Chloro-4,6-dimethoxy-1,3,5-triazine

2-Chloro-4,6-dimethoxy-1,3,5-triazine

CAS No.
3140-73-6
Chemical Name:
2-Chloro-4,6-dimethoxy-1,3,5-triazine
Synonyms
CDMT;AKOS 89995;CDMT 2-Chloro-4,6-diMethoxy-1,3,5-triazine;Chlorodimethoxytriazine;NSC 46520;6-diMethoxy-1;5-triazine (CDMT);2-Chloro-4,6-dimetho;2-Chloro-4,6-dimethoxy-1;2-CHLORO-4,6-DIMETHOXY-TRIAZINE
CBNumber:
CB4775597
Molecular Formula:
C5H6ClN3O2
Molecular Weight:
175.57
MDL Number:
MFCD00075607
MOL File:
3140-73-6.mol
MSDS File:
SDS
Last updated:2024-10-08 11:27:59

2-Chloro-4,6-dimethoxy-1,3,5-triazine Properties

Melting point 71-74 °C (lit.)
Boiling point 99-100 °C (1 mmHg)
Density 1.7917 (rough estimate)
vapor pressure 5.8Pa at 25℃
refractive index 1.5870 (estimate)
Flash point 99-100°C/1mm
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform, Methanol
form Crystalline Powder
pka 0.33±0.10(Predicted)
color White to almost white
Water Solubility insoluble
BRN 148988
InChIKey GPIQOFWTZXXOOV-UHFFFAOYSA-N
LogP 2.105 at 25℃
CAS DataBase Reference 3140-73-6(CAS DataBase Reference)
FDA UNII 6KB2H8FE5Q

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37-36
RIDADR  UN3077
WGK Germany  3
HS Code  29339900
NFPA 704
1
2 0

2-Chloro-4,6-dimethoxy-1,3,5-triazine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 375217 2-Chloro-4,6-dimethoxy-1,3,5-triazine 97% 3140-73-6 5g $63.7 2024-03-01 Buy
TCI Chemical C1676 2-Chloro-4,6-dimethoxy-1,3,5-triazine >97.0%(HPLC)(T) 3140-73-6 5g $20 2024-03-01 Buy
TCI Chemical C1676 2-Chloro-4,6-dimethoxy-1,3,5-triazine >97.0%(HPLC)(T) 3140-73-6 25g $39 2024-03-01 Buy
Alfa Aesar B24474 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98% 3140-73-6 5g $43.65 2024-03-01 Buy
Alfa Aesar B24474 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98% 3140-73-6 25g $126 2024-03-01 Buy
Product number Packaging Price Buy
375217 5g $63.7 Buy
C1676 5g $20 Buy
C1676 25g $39 Buy
B24474 5g $43.65 Buy
B24474 25g $126 Buy

2-Chloro-4,6-dimethoxy-1,3,5-triazine Chemical Properties,Uses,Production

Chemical Properties

white to almost white crystalline powder

Uses

2-Chloro-4,6-dimethoxy-1,3,5-triazine may be used in the following studies:

  • The specific labeling of streptavidin by the modular method for affinity labeling (MoAL).
  • The preparation of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, via reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine.
  • The preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts, via reaction with various tertiary amines.
  • The synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, via coupling with N-methylmorpholine in THF.

Uses

2-Chloro-4,6-dimethoxy-1,3,5-triazine is used as a peptide coupling agent for the purification of peptides. It is used in the synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride through coupling with N-methylmorpholine in tetrahydrofuran. Further, it plays an important role in the production of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, through reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine. In addition to this, it is involved in the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts through reaction with various tertiary amines.

General Description

2-Chloro-4,6-dimethoxy-1,3,5-triazine is a stable, yet highly reactive, peptide coupling agent. It is reported as useful coupling reagent for the purification of peptides. Catalytic amide-forming reactions of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported. Procedure for the preparation of multikilogram quantities of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.

Synthesis

A preparation method of 2-chloro-4,6-dimethoxy-1,3,5-triazine comprises the following steps: using cyanuric chloride and sodium methoxide solid as reaction raw materials and N, N-dimethylformamide as a reaction solvent, gradually heating to obtain a 2-chloro-4,6-dimethoxy-1,3,5-triazine crude product, and finally, recrystallizing with heptane for purification. The reaction temperature is controlled to prepare the product, and the yield is up to 91%.

2-Chloro-4,6-dimethoxy-1,3,5-triazine Preparation Products And Raw materials

Global( 558)Suppliers
Supplier Tel Email Country ProdList Advantage
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40066 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387 1057@dideu.com China 3958 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20287 58
airuikechemical co., ltd.
+undefined86-15315557071 sales02@sdzhonghuimaterial.com China 983 58
Watson Biotechnology Co.,Ltd
+86-18186686046 +86-18186686046 sales01@watsonbiotech.cn China 5822 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18777 58
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55

View Lastest Price from 2-Chloro-4,6-dimethoxy-1,3,5-triazine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CDMT  2-Chloro-4,6-dimethoxy-1,3,5-triazine pictures 2024-11-22 CDMT 2-Chloro-4,6-dimethoxy-1,3,5-triazine
3140-73-6
US $0.00-0.00 / kg 1kg 99% 20MT Watson Biotechnology Co.,Ltd
2-Chloro-4,6-dimethoxy-1,3,5-triazine/CDMT pictures 2024-11-22 2-Chloro-4,6-dimethoxy-1,3,5-triazine/CDMT
3140-73-6
US $0.00-0.00 / Kg/Drum 1KG 98%min 1000 KG WUHAN FORTUNA CHEMICAL CO., LTD
2-chloro-4,6-dimethoxy-1,3,5-triazine pictures 2024-10-15 2-chloro-4,6-dimethoxy-1,3,5-triazine
3140-73-6
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
1,3,5-Triazine, 2-chloro-4,6-dimethoxy- 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE 98% 2,4-Dimethoxy-6-chloro-1,3,5-triazine 2,4-Dimethoxy-6-chloro-s-triazine 4,6-Dimethoxy-2-chloro-1,3,5-triazine 2-Chloro-4,6-dimetho 5-triazine (CDMT) 6-diMethoxy-1 2-CHLORO 4,6-DIMETHOX 1,3,5-TRIAZINE 4-CHLORO-2,6-DIMETHOXY-1,3.5-TRIAZINE 4,6-DiMethoxy-2-chloro-s-triazine NSC 46520 2-Chloro-4,6-diMethoxy-1,3,5-triazine, 98% 25GR 2-Chloro-4,6-diMethoxy-1,3,5-triazine, 98% 5GR 2-Chloro-4,6-dimethoxy-s-triazine 2-chloro -4,6-twoMethoxy -1,3,5-three work 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE 2-CHLORO-4,6-DIMETHOXY-TRIAZINE 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE, 9 7% 2-CHLORO-4,6-DIMETHOXY-1,3,5-TRIAZINE (CDMT) oro-4,6-dimethoxy-1,3,5-triazine 2-Chlor-4,6-dimethoxy-1,3,5-triazin 2-Chloro-4,6-dimethoxy-1,3,5-triazine> 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 97%, for synthesis 2-Chloro-4,6 Dimethoxy-1,3,5 Triazine extrapure, 99% 2-Chloro-4,6-dimethoxy-1 CDMT 2-Chloro-4,6-diMethoxy-1,3,5-triazine CDMT AKOS 89995 Chlorodimethoxytriazine 3140-73-6 C5H6C1N3O2 C5H6ClN3O2 HETERO CHLORIDE Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Triazines Miscellaneous Aromatics Heterocycles Miscellaneous Reagents Biochemistry Coupling Reactions (Peptide Synthesis) Peptide Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Triazines TriazinesBuilding Blocks Starting Raw Materials & Intermediates bc0001