N-(tert-Butoxycarbonyl)-L-phenylalanine
- CAS No.
- 13734-34-4
- Chemical Name:
- N-(tert-Butoxycarbonyl)-L-phenylalanine
- Synonyms
- BOC-PHE-OH;BOC-PHE;BOC-L-PHE-OH;BOC-L-PHE;BOC-L-PHENYLALANINE;N-BOC-L-PHENYLALANINE;BOC-PHENYLALANINE;L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-;BOC-ph-OH;BOC Phenly Alanine
- CBNumber:
- CB4781305
- Molecular Formula:
- C14H19NO4
- Molecular Weight:
- 265.3
- MDL Number:
- MFCD00002663
- MOL File:
- 13734-34-4.mol
- MSDS File:
- SDS
Melting point | 85-87 °C(lit.) |
---|---|
Boiling point | 408.52°C (rough estimate) |
Density | 1.1356 (rough estimate) |
refractive index | 24.5 ° (C=1, EtOH) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in methanol, dichloromethane, dimethylformamide and N-methyl-2-pyrrolidone. |
form | Fine Crystalline Powder |
pka | 3.88±0.10(Predicted) |
color | White |
optical activity | [α]20/D +25±1°, c = 1% in ethanol |
BRN | 2219729 |
CAS DataBase Reference | 13734-34-4(CAS DataBase Reference) |
EPA Substance Registry System | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- (13734-34-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P271 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 36-22-36/37/38-20/21/22 | |||||||||
Safety Statements | 39-26-36-24/25 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29242990 | |||||||||
NFPA 704 |
|
N-(tert-Butoxycarbonyl)-L-phenylalanine price More Price(55)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.53006 | Boc-Phe-OH Novabiochem? | 13734-34-4 | 25g | $56.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.53006 | Boc-Phe-OH Novabiochem? | 13734-34-4 | 100g | $129 | 2024-03-01 | Buy |
Sigma-Aldrich | 15480 | Boc-Phe-OH ≥99.0% (T) | 13734-34-4 | 5g | $23.52 | 2024-03-01 | Buy |
Sigma-Aldrich | 15480 | Boc-Phe-OH ≥99.0% (T) | 13734-34-4 | 25g | $107 | 2024-03-01 | Buy |
TCI Chemical | B1332 | N-(tert-Butoxycarbonyl)-L-phenylalanine >99.0%(T) | 13734-34-4 | 5g | $16 | 2024-03-01 | Buy |
N-(tert-Butoxycarbonyl)-L-phenylalanine Chemical Properties,Uses,Production
Chemical Properties
N-(tert-Butoxycarbonyl)-L-phenylalanine is white fine crystalline powder
Uses
N-(tert-Butoxycarbonyl)-L-phenylalanine is used in enantioselective hydrolysis of amino acid esters. Acts as an inhibitor of gastric acid secretion.
Uses
N-Boc-L-phenylalanine is a derivative of Phenylalanine used in enantioselective hydrolysis of amino acid esters.
Preparation
Sodium hydroxide (4.4 g, 0.11 mol) was placed in a flask, and dissolved in water (110 mL). Phenylalanine (16.5 g, 0.1 mol) was added, the suspension was stirred until a solution was obtained, and then tert-butanol (75 mL) was added. Boc2O (22.3 g, 0.12 mol) was then added with stirring over a period of 1 h, keeping the mixture near 0 ℃. A white precipitate was produced, and at the end of the addition the pH had dropped to 7.5–8.5. The mixture was then carefully acidified by the slow, continuous addition of saturated citric acid to give the product N-tert-butoxycarbonyl-L-phenylalanine (21.5 g, 81%); mp 85℃; [a]21D = t25:5 (c = 1, ethanol).
N-(tert-Butoxycarbonyl)-L-phenylalanine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18153 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 | daisy@enlaibio.com | China | 1106 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20286 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29791 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32957 | 60 |
AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 988 | 58 |
View Lastest Price from N-(tert-Butoxycarbonyl)-L-phenylalanine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-28 | Boc-Phe-OH
13734-34-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
2024-11-27 | Boc-Phe-OH
13734-34-4
|
US $0.00 / Kg/Drum | 1KG | 98%min | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-11-01 | N-(tert-Butoxycarbonyl)-L-phenylalanine
13734-34-4
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Weibang Biotechnology Co., Ltd |
- Boc-Phe-OH
13734-34-4
- US $0.00-0.00 / kg
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
- Boc-Phe-OH
13734-34-4
- US $0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- N-(tert-Butoxycarbonyl)-L-phenylalanine
13734-34-4
- US $0.00-0.00 / KG
- 99%
- Hebei Weibang Biotechnology Co., Ltd