Exenatide acetate
- CAS No.
- 141732-76-5
- Chemical Name:
- Exenatide acetate
- Synonyms
- AI315415;Exenatide;AI3 15415;AI3-15415;Extendin-4;Exenatide-d5;Unii-9p1872D4ol;EXENATIDE ACETATE;exendin-4, PC-DAC;Exennatide Acetate
- CBNumber:
- CB4789871
- Molecular Formula:
- C186H286N50O62S
- Molecular Weight:
- 4244.60796
- MDL Number:
- MFCD08704781
- MOL File:
- 141732-76-5.mol
- MSDS File:
- SDS
Melting point | >209°C (dec.) |
---|---|
storage temp. | Refrigerator, under inert atmosphere |
solubility | Acetonitrile (Slightly), Water (Slightly) |
form | Solid |
color | White to Off-White |
Sequence | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
CAS DataBase Reference | 141732-76-5(CAS DataBase Reference) |
FDA UNII | 9P1872D4OL |
NCI Drug Dictionary | exenatide |
ATC code | A10BJ01 |
Exenatide acetate price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | E957300 | ExenatideAcetate | 141732-76-5 | 5mg | $175 | 2021-12-16 | Buy |
ChemScene | CS-0106996 | Enfuvirtide(acetate) 98.91% | 141732-76-5 | 25mg | $228 | 2021-12-16 | Buy |
Biosynth Carbosynth | FE23212 | Exenatide acetate | 141732-76-5 | 50mg | $333 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611418 | Exenatide | 141732-76-5 | 5mg | $345.1 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611417 | Exenatide acetate | 141732-76-5 | 5mg | $345.1 | 2021-12-16 | Buy |
Exenatide acetate Chemical Properties,Uses,Production
Chemical Properties
Exenatide acetate is White Solid
Uses
Application of exenatide acetate causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acetate acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide acetate augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide acetate has found use as a medication of diabetes II.
Uses
A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Clinical Use
39-peptide known as an incretin mimetic; an agonist of glucagon-like peptide-1, used adjunctively in type II diabetes mellitus.
Drug interactions
Potentially hazardous interactions with other drugs Anticoagulants: possibly enhances anticoagulant effect of warfarin. Other nephrotoxins: avoid concomitant use.
Metabolism
Exenatide is eliminated through the kidneys by glomerular filtration followed by proteolytic degradation.
Exenatide acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shandong Huizhihan Supply Chain Co., Ltd | +8613363081709 | 3957328362@qq.com | China | 300 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | cui56813@163.com | China | 110 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8615689548120 | linda@zhongda-biotech.com | China | 193 | 58 |
Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2943 | 58 |
Dorne Chemical Technology co. LTD | +86-86-13583358881 +8618560316533 | Ethan@dornechem.com | China | 3097 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 264 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
Shandong Huisheng Import & Export Co., Ltd. | +86-13176845580 +86-13176845580 | da@zhongda-biotech.com | China | 232 | 58 |
Anhui Zhongda Biotechnology Co., Ltd | +8619956560829 | justine@zhongda-biotech.com | China | 286 | 58 |
View Lastest Price from Exenatide acetate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-12-22 | Exenatide acetate
141732-76-5
|
US $1.00 / g | 1g | 99% | 100kg | Dorne Chemical Technology co. LTD | ||
2024-12-20 | Exenatide Acetate
141732-76-5
|
US $0.00-0.00 / BOX | 1BOX | 99 | 50000KG/month | Shanghai Affida new material science and technology center | ||
2024-12-17 | Exenatide Acetate
141732-76-5
|
US $30.00 / box | 1box | 98% | 5000box | hebei hongtan Biotechnology Co., Ltd |
- Exenatide acetate
141732-76-5
- US $1.00 / g
- 99%
- Dorne Chemical Technology co. LTD
- Exenatide Acetate
141732-76-5
- US $0.00-0.00 / BOX
- 99
- Shanghai Affida new material science and technology center
- Exenatide Acetate
141732-76-5
- US $30.00 / box
- 98%
- hebei hongtan Biotechnology Co., Ltd
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